Generating highly polarized nuclear spins in solution using dynamic nuclear polarization

J Wolber, F Ellner, B Fridlund, A Gram… - Nuclear Instruments and …, 2004 - Elsevier
A method to generate strongly polarized nuclear spins in solution has been developed,
using Dynamic Nuclear Polarization (DNP) at a temperature of 1.2 K, and at a field of 3.354 …

Increase in signal-to-noise ratio of> 10,000 times in liquid-state NMR

JH Ardenkjær-Larsen, B Fridlund… - Proceedings of the …, 2003 - National Acad Sciences
A method for obtaining strongly polarized nuclear spins in solution has been developed. The
method uses low temperature, high magnetic field, and dynamic nuclear polarization (DNP) …

Pulsed dynamic nuclear polarization with trityl radicals

G Mathies, S Jain, M Reese… - The journal of physical …, 2016 - ACS Publications
Continuous-wave (CW) dynamic nuclear polarization (DNP) is now established as a method
of choice to enhance the sensitivity in a variety of NMR experiments. Nevertheless, there …

Dynamic nuclear polarization of small labelled molecules in frozen water–alcohol solutions

F Kurdzesau, B Van Den Brandt… - Journal of Physics D …, 2008 - iopscience.iop.org
In recent years methods of creating'hyperpolarized'substances have gained considerable
attention in biomedical magnetic resonance and dynamic nuclear polarization (DNP) is one …

[HTML][HTML] An automated system for fast transfer and injection of hyperpolarized solutions

M Ceillier, O Cala, T El Daraï, SF Cousin… - Journal of Magnetic …, 2021 - Elsevier
Dissolution dynamic nuclear polarization (dDNP) has become a hyperpolarization method of
choice for enhancing nuclear magnetic resonance (NMR) signals. Nuclear spins are …

Design and performance of a DNP prepolarizer coupled to a rodent MRI scanner

A Comment, B van den Brandt… - … Resonance Part B …, 2007 - Wiley Online Library
For most of the last forty years, the techniques of Dynamic Nuclear Polarization (DNP) have
been confined to particle‐physics laboratories building polarized targets, but recently it has …

High frequency (140 GHz) dynamic nuclear polarization: polarization transfer to a solute in frozen aqueous solution

GJ Gerfen, LR Becerra, DA Hall, RG Griffin… - The Journal of …, 1995 - pubs.aip.org
Dynamic nuclear polarization (DNP) transfers the large polarization of unpaired electrons to
nuclei and thus significantly enhances the signal strength in nuclear magnetic resonance …

High frequency dynamic nuclear polarization: New directions for the 21st century

RG Griffin, TM Swager, RJ Temkin - Journal of magnetic resonance, 2019 - Elsevier
Dynamic nuclear polarization (DNP) is a technique that permits the sensitivity of nuclear
magnetic resonance (NMR) experiments to be enhanced by a factor of (γ e/γ n) where the γ's …

Dynamic polarization of 13C nuclei in solid 13C labeled pyruvic acid

W Meyer, J Heckmann, C Hess, E Radtke… - Nuclear Instruments and …, 2011 - Elsevier
Dynamic nuclear polarization (DNP) has proved to be one of the most effective methods to
increase the nuclear spin polarization in inorganic as well as organic materials since several …

High-frequency dynamic nuclear polarization in the nuclear rotating frame

CT Farrar, DA Hall, GJ Gerfen, M Rosay… - Journal of Magnetic …, 2000 - Elsevier
A proton dynamic nuclear polarization (DNP) NMR signal enhancement (ϵ) close to thermal
equilibrium, ϵ= 0.89, has been obtained at high field (B0= 5 T, νepr= 139.5 GHz) using 15 …