Heterozygous mutations in the histone lysine acetyltransferase gene KAT6B
(MYST4/MORF/QKF) underlie neurodevelopmental disorders, but the mechanistic roles of …

Lysine acetyltransferase 8, also known as KAT8, is an enzyme involved in epigenetic
regulation, primarily recognized for its ability to modulate histone acetylation. This review …

Chromatin remodeling is fundamental for the dynamical changes in transcriptional programs
that occur during development and stem cell differentiation. The histone acetyltransferase …

In the conventional model of transcriptional activation, transcription factors bind to response
elements and recruit co-factors, including histone acetyltransferases. Contrary to this model …

Epigenetic integrity is critical for many eukaryotic cellular processes. An important question
is how different epigenetic regulators control development and influence disease. Lysine …

The lysine acetyltransferases type 3 (KAT3) family members CBP and p300 are important
transcriptional co-activators, but their specific functions in adult post-mitotic neurons remain …

The human lysine acetyltransferases KAT3A (CREBBP) and KAT3B (EP300) are essential
enzymes in gene regulation in the nucleus. Their ubiquitous expression in metazoan cell …

Regulation of chromatin structure is critical for cell type-specific gene expression. Many
chromatin regulatory complexes exist in several different forms, due to alternative splicing …

Embryo quality is strongly associated with subsequent embryonic developmental efficiency.
However, the detailed function of lysine acetyltransferase 8 (KAT8) during early embryonic …

The lysine acetyltransferase KAT6A (MOZ, MYST3) belongs to the MYST family of chromatin
regulators, facilitating histone acetylation. Dysregulation of KAT6A has been implicated in …