Age‐related differences in the immune response could contribute to determine the spectrum of severity of COVID‐19

G Costagliola, E Spada… - … inflammation and disease, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19), can present with a wide spectrum of
severity. Elderly patients with cardiac, pulmonary and metabolic comorbidities are more …

Understanding COVID-19 in children: immune determinants and post-infection conditions

GA Rotulo, P Palma - Pediatric research, 2023 - nature.com
Coronavirus disease 2019 in children presents with milder clinical manifestations than in
adults. On the other hand, the presence of a wide range of inflammatory manifestations …

The role of dysregulated immune responses in COVID-19 pathogenesis

S Tahaghoghi-Hajghorbani, P Zafari, E Masoumi… - Virus research, 2020 - Elsevier
Abstract The coronavirus disease-2019 (COVID-19) which caused by severe acute
respiratory syndrome-related coronavirus (SARS-CoV-2), is a pandemic threat to global …

COVID-19 pathophysiology: A review

K Yuki, M Fujiogi, S Koutsogiannaki - Clinical immunology, 2020 - Elsevier
In December 2019, a novel coronavirus, now named as SARS-CoV-2, caused a series of
acute atypical respiratory diseases in Wuhan, Hubei Province, China. The disease caused …

Immune response to SARS-CoV-2 in children: A review of the current knowledge

F Filippatos, EB Tatsi, A Michos - Pediatric Investigation, 2021 - mednexus.org
Host immune responses to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
especially in children, are still under investigation. Children with coronavirus disease 2019 …

Insight into the pediatric and adult dichotomy of COVID‐19: age‐related differences in the immune response to SARS‐CoV‐2 infection

A Fialkowski, Y Gernez, P Arya… - Pediatric …, 2020 - Wiley Online Library
The difference in morbidity and mortality between adult and pediatric coronavirus disease
2019 infections is dramatic. Understanding pediatric‐specific acute and delayed immune …

COVID-19 in immunosuppressed children

E Nicastro, L Verdoni, LR Bettini, G Zuin… - Frontiers in …, 2021 - frontiersin.org
Following the spread of the SARS-CoV-2 infection and coronavirus disease 2019 (COVID-
19) to a global pandemic, concerns have arisen for the disease impact in at-risk populations …

Pathophysiology of COVID-19: why children fare better than adults?

N Dhochak, T Singhal, SK Kabra, R Lodha - The Indian Journal of …, 2020 - Springer
The world is facing Coronavirus Disease-2019 (COVID-19) pandemic, which is causing a
large number of deaths and burden on intensive care facilities. It is caused by Severe Acute …

Age-related differences in immunological responses to SARS-CoV-2

LSY Wong, EXL Loo, AYH Kang, HX Lau… - The Journal of Allergy …, 2020 - Elsevier
There is a striking age-related disparity in the prevalence and severity of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2)-induced coronavirus disease 2019 …

Recovering or persisting: the immunopathological features of SARS-CoV-2 infection in children

D Buonsenso, P Valentini, C De Rose… - Journal of Clinical …, 2022 - mdpi.com
Background. The profile of cellular immunological responses of children across the
spectrum of COVID-19, ranging from acute SARS-CoV-2 infection to full recovery or Long …