Development of a Highly Sensitive Method for Detection of Clarithromycin-Resistant Helicobacter pylori from Human Feces

E Rimbara, N Noguchi, T Yamaguchi, K Narui… - Current …, 2005 - Springer
Gastric infection of clarithromycin (CAM)-resistant Helicobacter pylori is one of the major
causes of failure to eradicate this organism. A noninvasive and useful method for the …

Detection of mixed clarithromycin-resistant and -susceptible Helicobacter pylori using nested PCR and direct sequencing of DNA extracted from faeces

N Noguchi, E Rimbara, A Kato… - Journal of medical …, 2007 - microbiologyresearch.org
The major cause of chemotherapy failure in patients with chronic gastritis and peptic ulcers
caused by Helicobacter pylori is clarithromycin (CAM) resistance due to a mutation in the …

A novel stool PCR test for Helicobacter pylori may predict clarithromycin resistance and eradication of infection at a high rate

E Beckman, I Saracino, G Fiorini, C Clark… - Journal of clinical …, 2017 - Am Soc Microbiol
Clarithromycin-based regimens are commonly used as a first-line therapy for Helicobacter
pylori-positive patients; however, resistance to clarithromycin has led to treatment failures …

[HTML][HTML] Real-time PCR for Helicobacter pylori quantification and detection of clarithromycin resistance in gastric tissue from patients with gastrointestinal disorders

M Kargar, S Ghorbani-Dalini, A Doosti… - Research in microbiology, 2012 - Elsevier
Helicobacter pylori gram-negative bacteria commonly infect the human gastrointestinal (GI)
tract and are readily diagnosed by endoscopy. H. pylori infection causes a broad range of …

[HTML][HTML] A novel RT-PCR for the detection of Helicobacter pylori and identification of clarithromycin resistance mediated by mutations in the 23S rRNA gene

JJ Redondo, PM Keller, R Zbinden… - … microbiology and infectious …, 2018 - Elsevier
In this study we evaluated the commercially available LightMix® RT-PCR assay for
Helicobacter pylori detection and identification of clarithromycin (CLR) resistance in culture …

Development and Validation of Multiplex Quantitative PCR Assay for Detection of Helicobacter pylori and Mutations Conferring Resistance to Clarithromycin and …

H Binmaeil, A Hanafiah, I Mohamed Rose… - Infection and Drug …, 2021 - Taylor & Francis
Aims and Objectives More than half of the world's population is infected with Helicobacter
pylori, which can cause chronic gastritis. WHO has regarded clarithromycin-resistant H …

Detection of clarithromycin-resistant Helicobacter pylori in clinical specimens by molecular methods: A review

SH Xuan, LP Wu, YG Zhou, M Xiao - Journal of global antimicrobial …, 2016 - Elsevier
Various molecular methods have been developed to rapidly detect clarithromycin (CLR)
resistance in Helicobacter pylori isolates in clinical specimens. All of these assays for …

Novel Real-Time PCR Assay for Detection of Helicobacter pylori Infection and Simultaneous Clarithromycin Susceptibility Testing of Stool and Biopsy Specimens

C Schabereiter-Gurtner, AM Hirschl… - Journal of clinical …, 2004 - Am Soc Microbiol
ABSTRACT A biprobe real-time PCR protocol, followed by hybridization melting point
analysis, to detect point mutations in the 23S rRNA gene of Helicobacter pylori associated …

PCR-Based Diagnosis of Helicobacter pylori Infection and Real-Time Determination of Clarithromycin Resistance Directly from Human Gastric Biopsy Samples

SA Chisholm, RJ Owen, EL Teare… - Journal of Clinical …, 2001 - Am Soc Microbiol
ABSTRACT A novel PCR detection assay that amplifies the Helicobacter pylori-specific
vacuolating cytotoxin gene (vacA) and thus enables rapid diagnosis of infection is …

[HTML][HTML] Real-time polymerase chain reaction for the detection of Helicobacter pylori and clarithromycin resistance

JH Noh, JY Ahn, J Choi, YS Park, HK Na, JH Lee… - Gut and …, 2023 - ncbi.nlm.nih.gov
Methods A total of 70 specimens with confirmed H. pylori infection in culture were enrolled
and analyzed in this prospective study. All specimens were subjected to RT-PCR assay …