Cartilage destruction in rheumatoid arthritis (RA) occurs primarily in the pannus-cartilage
interface. The close contact of the synovium-cartilage interface implicates crosstalk between …

The phenotypic change of chondrocytes and the interplay between cartilage and
subchondral bone in osteoarthritis (OA) has received much attention. Structural changes …

Background Osteoarthritis (OA) is a chronic degenerative joint disease and the most
frequent type of arthritis. This study aimed to identify the key miRNAs and genes associated …

Osteoarthritis occurs when protective cartilage of bones worn out. Similarlty, cartilage
damage occurs mainly in the pannus cartilage in rheumatoid arthritis. It is a potentially …

Objectives To investigate microRNA-320a-related differentially expressed genes (DEGs)
and pathways in osteoarthritis (OA) by bioinformatic analysis. Methods The target genes of …

Rheumatoid arthritis (RA) and osteoarthritis (OA) are the two most common debilitating joint
disorders and although both share similar clinical manifestations, the pathogenesis of each …

Background: Osteoarthritis (OA) is one of the main causes of disability in the elderly
population, accompanied by a series of underlying pathologic changes, such as cartilage …

Numerous studies have focused on osteoarthritis (OA) cartilage injuries, with observations of
abnormalities in microRNA (miRNA) expression levels. The aim of the present study was to …

Purpose: Currently, the early diagnosis and treatment of osteoarthritis (OA) remain a
challenge. In the present study, we attempted to explore potential biomarkers for the …

This study aimed to explore crucial genes that contribute to the development of rheumatoid
arthritis (RA). Three GSE77298, GSE55457, and GSE55235 data sets were used to analyze …