[HTML][HTML] Metabolite profile of COVID-19 revealed by UPLC-MS/MS-based widely targeted metabolomics

J Liu, ZB Li, QQ Lu, Y Yu, SQ Zhang, PF Ke… - Frontiers in …, 2022 - frontiersin.org
The metabolic characteristics of COVID-19 disease are still largely unknown. Here, 44
patients with COVID-19 (31 mild COVID-19 patients and 13 severe COVID-19 patients), 42 …

[HTML][HTML] Novel potential metabolic biomarker panel for early detection of severe COVID-19 using full-spectrum metabolome and whole-transcriptome analyses

ZB Li, J Liu, SQ Zhang, Y Yu, HF Liang, QQ Lu… - Signal transduction and …, 2022 - nature.com
The mortality rate of severe coronavirus disease 2019 (COVID-19) is high, and there is no
universally accepted method to predict its occurrence. COVID-19 pneumonia can be …

Metabolite reanalysis revealed potential biomarkers for COVID-19: a potential link with immune response

X Chen, M Gu, T Li, Y Sun - Future Microbiology, 2021 - Future Medicine
Aim: To understand the pathological progress of COVID-19 and to explore the potential
biomarkers. Background: The COVID-19 pandemic is ongoing. There is metabolomics …

[HTML][HTML] Sera metabolomics characterization of patients at different stages in wuhan identifies critical biomarkers of COVID-19

M Gu, H Pan, Y Yuan, X Zhou, L Chen… - Frontiers in Cellular …, 2022 - frontiersin.org
We have witnessed a two-year-long global rampage of COVID-19 caused by the wide
spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However …

[HTML][HTML] Metabolic profiling at COVID-19 onset shows disease severity and sex-specific dysregulation

FC Ceballos, A Virseda-Berdices, S Resino… - Frontiers in …, 2022 - frontiersin.org
Background metabolic changes through SARS-CoV-2 infection has been reported but not
fully comprehended. This metabolic dysregulation affects multiple organs during COVID-19 …

The serum metabolome of COVID-19 patients is distinctive and predictive

D Shi, R Yan, L Lv, H Jiang, Y Lu, J Sheng, J Xie, W Wu… - Metabolism, 2021 - Elsevier
Background Metabolism is critical for sustaining life, immunity and infection, but its role in
COVID-19 is not fully understood. Methods Seventy-nine COVID-19 patients, 78 healthy …

Understanding the pathophysiological changes via untargeted metabolomics in COVID‐19 patients

HO Doğan, O Şenol, S Bolat, ŞN Yıldız… - Journal of medical …, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is an infectious respiratory disease caused
by a new strain of the coronavirus. There is limited data on the pathogenesis and the cellular …

MetaboliteCOVID: A manually curated database of metabolite markers for COVID-19

L Ren, L Ning, Y Yang, T Yang, X Li, S Tan, P Ge… - Computers in Biology …, 2023 - Elsevier
In the realm of unraveling COVID-19's intricacies, numerous metabolomic investigations
have been conducted to discern the unique metabolic traits exhibited within infected …

[HTML][HTML] Metabolomics study of COVID-19 patients in four different clinical stages

A Valdés, LO Moreno, SR Rello, A Orduña… - Scientific reports, 2022 - nature.com
Abstract SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is the coronavirus
strain causing the respiratory pandemic COVID-19 (coronavirus disease 2019). To …

1H qNMR-Based Metabolomics Discrimination of Covid-19 Severity

BSB Correia, VG Ferreira, PMFD Piagge… - Journal of Proteome …, 2022 - ACS Publications
The coronavirus disease 2019 (Covid-19), which caused respiratory problems in many
patients worldwide, led to more than 5 million deaths by the end of 2021. Experienced …