New Delhi metallo-β-lactamases (NDMs), the recent additions to metallo-β-lactamases
(MBLs), pose a serious public health threat due to its highly efficient hydrolysis of β-lactam …

ABSTRACT Metallo‐β‐lactamases (MBLs) hydrolyze most β‐lactam antibiotics, and bacteria
containing this kind of enzyme pose a serious threat to the public health. The newly …

New Delhi metallo-β-lactamase-1 exhibits a broad substrate profile for hydrolysis of the
penicillin, cephalosporin and 'last resort'carbapenems, and thus confers bacterial resistance …

Carbapenems are one of the last lines of defense for Gram-negative pathogens, such as
members of the Enterobacteriaceae. Despite the fact that most carbapenems are resistant to …

The worldwide emergence of New Delhi metallo-β-lactamase-1 (NDM-1) as a
carbapenemase able to hydrolyze nearly all available β-lactam antibiotics has characterized …

Carbapenem-resistant Enterobacteriaceae threaten human health, since carbapenems are
last resort drugs for infections by such organisms. Metallo-β-lactamases (MβLs) are the main …

The β-lactam antibiotics have long been a cornerstone for the treatment of bacterial disease.
Recently, a readily transferable antibiotic resistance factor called the New Delhi metallo-β …

Cephalosporins constitute a large class of β-lactam antibiotics clinically used as
antimicrobial drugs. New Dehli metallo-β-lactamase (NDM-1) poses a global threat to …

Abstract The New Delhi metallo‐β‐lactamase (NDM‐1) is involved in the emerging antibiotic
resistance problem. Development of metallo‐β‐lactamases (MBLs) inhibitors has proven …

Gram-negative Enterobacteriaceae with resistance to carbapenem conferred by New Delhi
metallo-β-lactamase 1 (NDM-1) are a type of newly discovered antibioticresistant bacteria …