KLHL14: a novel prognostic biomarker and therapeutic target for ovarian cancer

X Wang, R Sun, X Hong, C Chen, Y Ding - Journal of Oncology, 2022 - Wiley Online Library
Ovarian cancer (OV) is a gynaecological malignancy that poses a serious risk to the health
status of women. To date, effective molecular markers are unavailable for the diagnosis and …

[HTML][HTML] KLHL14, an ovarian and endometrial-specific gene, is over-expressed in ovarian and endometrial cancer

M Han, H Yang, Q Lin - Mathematical Biosciences and Engineering, 2020 - aimspress.com
Ovarian cancer (OC) and endometrial cancer (EC) are two types of the most frequent
gynecological malignancies worldwide. However, the prognosis of OC and EC patients …

[HTML][HTML] Kelch-like protein 14 promotes proliferation and migration of ovarian cancer cells

Z Chen, M Wu, J Liu - International Journal of Clinical and …, 2020 - ncbi.nlm.nih.gov
Abstract Kelch-like protein 14 (KLHL14) belongs to the Kelch gene family, which interacts
with TorsinA and is associated with dystonia symptoms. However, the effect of KLHL14 on …

Analysis of expression and prognosis of KLK7 in ovarian cancer

E Chen, H Zhu, Y Yang, L Wang, J Zhang, Y Han… - Open …, 2020 - degruyter.com
Background Ovarian cancer is one of the common malignant tumors in female reproductive
organs. Kallikrein-related peptidase (KLK) 7 is a secreted serine peptidase that is related to …

Krupple-like factor 5 is a potential therapeutic target and prognostic marker in epithelial ovarian cancer

AK Siraj, P Pratheeshkumar, SP Divya… - Frontiers in …, 2020 - frontiersin.org
Epithelial ovarian cancer (EOC) is the most lethal gynecological malignancy. Despite current
therapeutic and surgical options, advanced EOC shows poor prognosis. Identifying novel …

KLF7: a new candidate biomarker and therapeutic target for high-grade serous ovarian cancer

M De Donato, G Babini, S Mozzetti, M Buttarelli… - Journal of Experimental …, 2020 - Springer
Background In spite of great progress in the surgical and clinical management, until now no
significant improvement in overall survival of High-Grade Serous Ovarian Cancer (HGSOC) …

[HTML][HTML] Diagnostic value of KLK6 as an ovarian cancer biomarker: A meta-analysis

F Yang, ZD Hu, Y Chen, CJ Hu - Biomedical reports, 2016 - spandidos-publications.com
Abstract Kallikrein-related peptidase 6 (KLK6) is a new potential serum biomarker of ovarian
cancer. The aim of the present study was to assess the diagnostic value of KLK6 …

KLHL5 is a prognostic-related biomarker and correlated with immune infiltrates in gastric cancer

Q Wu, G Yin, J Lei, J Tian, A Lan, S Liu - Frontiers in Molecular …, 2020 - frontiersin.org
Background: KLHL5 (Kelch Like Family Member 5) is differentially expressed in gastric
cancer, but its correlation with prognosis and functioning mechanism in gastric cancer …

KLK6 and KLK13 predict tumor recurrence in epithelial ovarian carcinoma

NMA White, M Mathews, GM Yousef, A Prizada… - British journal of …, 2009 - nature.com
Background: The human kallikrein-related peptidase family consists of 15 genes. Twelve of
these genes are overexpressed in ovarian cancer and may represent potential markers for …

Advanced high-grade serous ovarian cancer: inverse association of KLK13 and KLK14 mRNA levels in tumor tissue and patients' prognosis

L Dettmar, N Ahmed, M Kotzsch, S Diersch… - Journal of cancer …, 2018 - Springer
Purpose Gene expression of a variety of the 15 members of the KLK serine protease family
is dysregulated in ovarian cancer. We aimed at determining the clinical relevance of KLK13 …