Background The podocyte is a remarkable cell type, which encases the capillaries of the
kidney glomerulus. Although mesodermal in origin it sends out axonal like projections that …

The renal corpuscle of the kidney comprises a glomerular vasculature embraced by
podocytes and supported by mesangial myofibroblasts, which ensure plasma filtration at the …

Podocytes do not remain fully differentiated when cultured, and they are difficult to image in
vivo, making the study of podocyte biology challenging. Zebrafish embryos are transparent …

A thorough characterization of the transcriptome and proteome of endogenous podocytes
has been hampered by low cell yields during isolation. Here we describe a double …

A critical event during kidney organogenesis is the differentiation of podocytes, specialized
epithelial cells that filter blood plasma to form urine. Podocytes derived from human …

Glomerular visceral epithelial cells (podocytes) are highly specialized cells found in the
vertebrate and invertebrate kidney and make up a major portion of the filtration barrier …

Podocytes and parietal epithelial cells (PECs) are among the few principal cell types within
the kidney glomerulus, the former serving as a crucial constituent of the kidney filtration …

During development, vertebrates form a progression of up to three different kidneys that are
comprised of functional units termed nephrons. Nephron composition is highly conserved …

Human genetic and in vivo studies have helped to define the critical importance of
podocytes for kidney function in health and disease. However, as in any other research …

Over the past two decades it has become increasing clear that injury and loss of podocytes
is an early and common clinical observation presented in many forms of glomerulopathy and …