Tests of adrenal insufficiency

JC Agwu, H Spoudeas, PC Hindmarsh… - Archives of Disease in …, 1999 - adc.bmj.com
AIM In suspected adrenal insufficiency, the ideal test for assessing the hypothalamo–
pituitary–adrenal axis is controversial. Therefore, three tests were compared in patients …

[HTML][HTML] Adrenal insufficiency–recognition and management

A Pazderska, SHS Pearce - Clinical Medicine, 2017 - Elsevier
Adrenal insufficiency is characterised by inadequate glucocorticoid production owing to
destruction of the adrenal cortex or lack of adrenocorticotropic hormone stimulation. In …

Pediatric adrenal insufficiency: diagnosis, management, and new therapies

SA Bowden, R Henry - International journal of pediatrics, 2018 - Wiley Online Library
Adrenal insufficiency may result from a wide variety of congenital or acquired disorders of
hypothalamus, pituitary, or adrenal cortex. Destruction or dysfunction of the adrenal cortex is …

New cutoffs for the biochemical diagnosis of adrenal insufficiency after ACTH stimulation using specific cortisol assays

BR Javorsky, H Raff, TB Carroll… - Journal of the …, 2021 - academic.oup.com
Context The normal cortisol response 30 or 60 minutes after cosyntropin (ACTH [1–24]) is
considered to be≥ 18 μg/dL (500 nmol/L). This threshold is based on older serum cortisol …

Adrenal insufficiency

E Charmandari, NC Nicolaides, GP Chrousos - The Lancet, 2014 - thelancet.com
Adrenal insufficiency is the clinical manifestation of deficient production or action of
glucocorticoids, with or without deficiency also in mineralocorticoids and adrenal androgens …

Adrenal insufficiency

R Kumar, WS Wassif - Journal of Clinical Pathology, 2022 - jcp.bmj.com
Adrenal insufficiency (AI), first described by Thomas Addison in 1855, is characterised by
inadequate hormonal production by the adrenal gland, which could either be primary, due to …

Predisposing factors for adrenal insufficiency

SR Bornstein - New England Journal of Medicine, 2009 - Mass Medical Soc
Clinicians must be aware of the growing list of causes and predisposing factors that may
lead to the life-threatening disorder of acute adrenal insufficiency. This review provides a …

Pediatric adrenal insufficiency: challenges and solutions

D Nisticò, B Bossini, S Benvenuto… - … and clinical risk …, 2022 - Taylor & Francis
Adrenal insufficiency is an insidious diagnosis that can be initially misdiagnosed as other life-
threatening endocrine conditions, as well as sepsis, metabolic disorders, or cardiovascular …

Autoimmune Addison's disease

C Betterle, L Morlin - Pediatric adrenal diseases, 2011 - karger.com
Primary adrenocortical insufficiency, or Addison's disease (AD), results from an adrenal
cortex hypofunction/dysfunction with a deficient production of glucocorticoids …

Primary adrenal insufficiency in children: Diagnosis and management

T Kirkgoz, T Guran - Best Practice & Research Clinical Endocrinology & …, 2018 - Elsevier
Primary adrenal insufficiency (PAI) is a life-threatening disorder of adrenal cortex which is
characterized by deficient biosynthesis of glucocorticoids, with or without deficiency in …