Immune classification and identification of prognostic genes for uveal melanoma based on six immune cell signatures

G Gao, Z Yu, X Zhao, X Fu, S Liu, S Liang, A Deng - Scientific Reports, 2021 - nature.com
Cutaneous melanoma could be treated by immunotherapy, which only has limited efficacy
on uveal melanoma (UM). UM immunotyping for predicting immunotherapeutic responses …

Construction and validation of a novel immunosignature for overall survival in uveal melanoma

C Gu, X Gu, Y Wang, Z Yao, C Zhou - Frontiers in Cell and …, 2021 - frontiersin.org
Objectives Uveal melanoma (UM) is the most common primary intraocular malignancy in
adults, and immune infiltration plays a crucial role in the prognosis of UM. This study aimed …

Identification of molecular subtyping system and four-gene prognostic signature with immune-related genes for uveal melanoma

F Xia, Z Yu, A Deng, G Gao - Experimental Biology and …, 2022 - journals.sagepub.com
Immunotherapy is the most promising treatment for uveal melanoma patients with
metastasis. Tumor microenvironment plays an essential role in tumor progression and …

The prognostic value of immune-related genes AZGP1, SLCO5A1, and CTF1 in Uveal melanoma

W Wang, S Wang - Frontiers in Oncology, 2022 - frontiersin.org
Objective Uveal melanoma (UM) is an aggressive malignancy with a poor prognosis and no
available effective treatment. Therefore, exploring a potential prognostic marker for UM …

Immunogenic profiling of metastatic uveal melanoma discerns a potential signature related to prognosis

J Wang, M Liu, J Sun, Z Zhang - Journal of Cancer Research and Clinical …, 2024 - Springer
Background Uveal melanoma (UM) is an aggressive intraocular malignant tumor. The
present study aimed to identify the key genes associated with UM metastasis and …

Identification and validation of an immune-relevant risk signature predicting survival outcome and immune infiltration in uveal melanoma

X Sun, Q Li, G Xu - International Ophthalmology, 2023 - Springer
Purpose The current study aimed to reveal a novel immune-related signature to evaluate
immune infiltration status and the survival outcome for patients with uveal melanoma (UM) …

[HTML][HTML] Identification of an immune-related signature for the prognosis of uveal melanoma

YZ Li, Y Huang, XY Deng, CS Tu - International Journal of …, 2020 - ncbi.nlm.nih.gov
AIM To construct an immune-related prognostic signature (IPS) that can distinguish and
predict prognosis in uveal melanoma (UM). METHODS The transcriptomic data and …

Landscape of infiltrated immune cell characterization in uveal melanoma to improve immune checkpoint blockade therapy

X Lv, M Ding, Y Liu - Frontiers in Immunology, 2022 - frontiersin.org
Background Numerous studies indicated that tumor-infiltrated immune cells (TIC) in the
microenvironment are substantially linked to immunotherapy response and cancer …

Identification of a prognostic six-immune-gene signature and a nomogram model for uveal melanoma

B Yang, Y Fan, R Liang, Y Wu, A Gu - BMC ophthalmology, 2023 - Springer
Background To identify an immune-related prognostic signature and find potential
therapeutic targets for uveal melanoma. Methods The RNA-sequencing data obtained from …

Identification of prognostic genes in uveal melanoma microenvironment

H Luo, C Ma - PLoS One, 2020 - journals.plos.org
Background Uveal melanoma (UM) is the most common primary intraocular malignancy in
adults. Many previous studies have demonstrated that the infiltrating of immune and stromal …