Inflammatory bowel disease (IBD) is presently one of the most investigated human
disorders. Expansion of knowledge of its pathophysiology has helped in developing novel …

A systems biology approach could potentially identify the central regulators (hubs) in the IBD
interactome and improve our understanding of the molecular mechanisms involved in IBD …

The continuing identification of several epigenetic, transcriptomic, proteomic, and
metabolomic alterations in patients with IBD reflects the complex nature of the disease and …

Although the prevalence of main idiopathic forms of inflammatory bowel disease (IBD) has
risen considerably over the last decades, their clinical features do not allow accurate …

Inflammatory bowel disease (IBD) is a chronic and life‐threating inflammatory disease of
gastroenteric tissue characterized by episodes of intestinal inflammation. The pathogenesis …

Crohn's disease and ulcerative colitis are prototypical complex diseases characterized by
chronic and heterogeneous manifestations, induced by interacting environmental, genomic …

The current understanding of inflammatory bowel disease (IBD) pathogenesis implicates a
complex interaction between host genetics, host immunity, microbiome, and environmental …

It is becoming increasingly evident that the old paradigm of disease pathogenesis where a
given genotype would determine a phenotype and this would lead to a particular disease is …

Microbe–host communication is essential to maintain vital functions of a healthy host, and its
disruption has been associated with several diseases, including Crohn's disease and …

In the last century, humanity has being increasingly affected by a large number of chronic
conditions that fall into two major categories: neoplastic and inflammatory diseases. Unlike …