Alzheimer's disease (AD) is a progressive neurodegenerative disorder that accounts for the
most cases of dementia, which is characterized by the deposition of dense plaques of …

Alzheimer's disease (AD) is a genetically complex disease whose pathogenesis is largely
influenced by genetic factors. Three decades of intensive research have yielded four …

Three decades of genetic research in Alzheimer disease (AD) have substantially broadened
our understanding of the pathogenetic mechanisms leading to neurodegeneration and …

Alzheimer's disease (AD) is a genetically complex and heterogeneous disorder. Recent
estimates suggest that possibly over 70% of the genetic variance for the disease remains …

Alzheimer's disease (AD) is a complex and heterogeneous neurodegenerative disorder,
classified as either early onset (under 65 years of age), or late onset (over 65 years of age) …

Genetic factors are involved in the aetiology of Alzheimer's disease (AD) in 25–40% of the
cases. In some cases AD clearly segregates as an autosomal dominant trait in families …

The rich and colorful history of gene discovery in Alzheimer's disease (AD) over the past
three decades is as complex and heterogeneous as the disease, itself. Twin and family …

Alzheimer's disease (AD) is a clinically heterogeneous neurodegenerative disease with a
strong genetic component. Several genes have been associated with AD risk for nearly 20 …

Until recently, the search for genes contributing to Alzheimer's disease (AD) had been slow
and disappointing, with the notable exception of the APOE ε4 allele, which increases risk …

Alzheimer disease (AD), a progressive and neurodegenerative disease, is the most common
form of dementia with high incidence in elderly people. Neuropathologically the disease is …