Over the past decade, research aiming to disentangle the genetic underpinnings of late-
onset Alzheimer's disease has mostly focused on the identification of common variants …

Alzheimer's disease (AD) is a major problem of health and disability, with a relevant
economic impact on our society. Despite important advances in pathogenesis, diagnosis …

Genetic factors have a variable impact on Alzheimer's Disease (AD), ranging from familial
forms that are transmitted in an autosomal dominant fashion to sporadic AD, where a …

Familial Alzheimer's disease (AD), mostly associated with early onset, is caused by
mutations in three genes (APP, PSEN1, and PSEN2) involved in the production of the …

The genetic underpinnings of Alzheimer's disease (AD) remain largely elusive despite early
successes in identifying three genes that cause early-onset familial AD (those that encode …

Alzheimer's's disease (AD) is a genetically complex disorder associated with multiple
genetic defects either mutational or of susceptibility. Current AD genetics does not explain in …

At present, the etiology of Alzheimer's disease (AD) is still unclear, but both genetic and non-
genetic factors are thought to take part in the etiopathogenesis of AD. Epidemiologic …

Alzheimer disease (AD), the major form of senile dementia, is rapidly becoming a major
health problem in developed countries since as populations live longer the number of …

Abstract Alzheimer's disease (AD), the main form of dementia in the elderly, is the most
common progressive neurodegenerative disease characterized by rapidly progressive …

Alzheimer's disease (AD) is the most common cause of dementia and accounts for one-half
to three-fourths of all cases of dementia. In the United States, AD is the leading cause of a …