[HTML][HTML] Liver-derived cell-free nucleic acids in plasma: Biology and applications in liquid biopsies

P Jiang, KCA Chan, YMD Lo - Journal of hepatology, 2019 - Elsevier
There is much global research interest surrounding the use of cell-free DNA (cfDNA) for
liquid biopsies. cfDNA-based non-invasive prenatal testing for foetal chromosomal …

Circulating cell-free nucleic acids: main characteristics and clinical application

M Szilágyi, O Pös, É Márton, G Buglyó… - International journal of …, 2020 - mdpi.com
Liquid biopsy recently became a very promising diagnostic method that has several
advantages over conventional invasive methods. Liquid biopsy may serve as a source of …

Epigenetic biomarkers in cell-free DNA and applications in liquid biopsy

W Gai, K Sun - Genes, 2019 - mdpi.com
Cell-free circulating DNA (cfDNA) in plasma has gained global interest as a diagnostic
material for noninvasive prenatal testing and cancer diagnosis, or the so-called “liquid …

Current and future perspectives of cell-free DNA in liquid biopsy

S Liu, J Wang - Current Issues in Molecular Biology, 2022 - mdpi.com
A liquid biopsy is a minimally invasive or non-invasive method to analyze a range of tumor
material in blood or other body fluids, including circulating tumor cells (CTCs), cell-free DNA …

[HTML][HTML] Liquid biopsy in patients with hepatocellular carcinoma: Circulating tumor cells and cell-free nucleic acids

W Okajima, S Komatsu, D Ichikawa… - World Journal of …, 2017 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC), with its high incidence and mortality rate, is one of the
most common malignant tumors. Despite recent development of a diagnostic and treatment …

Circulating cell-free DNA for cancer early detection

Q Gao, Q Zeng, Z Wang, C Li, Y Xu, P Cui, X Zhu, H Lu… - The Innovation, 2022 - cell.com
Effective screening modalities are currently available for only a small subset of cancers, and
they generally have suboptimal performance with complicated procedures. Therefore, there …

Characteristics, properties, and potential applications of circulating cell-free dna in clinical diagnostics: a focus on transplantation

K Sherwood, ET Weimer - Journal of immunological methods, 2018 - Elsevier
The initial discovery of cell-free DNA (cfDNA) in 1948 by Mandel and Metais has led to
numerous investigations evaluating the role of cfDNA in various disease states. cfDNA has …

The utility of repetitive cell-free DNA in cancer liquid biopsies

U Gezer, AJ Bronkhorst, S Holdenrieder - Diagnostics, 2022 - mdpi.com
Liquid biopsy is a broad term that refers to the testing of body fluids for biomarkers that
correlate with a pathological condition. While a variety of body-fluid components (eg …

Cell-free DNA: applications in different diseases

R Ranucci - Cell-free DNA as Diagnostic Markers: Methods and …, 2019 - Springer
Since its discovery in human blood plasma about 70 years ago, circulating cell-free DNA
(cfDNA) has become an attractive subject of research as noninvasive disease biomarker …

Cell-free DNA fragmentomics in liquid biopsy

SC Ding, YMD Lo - Diagnostics, 2022 - mdpi.com
Cell-free DNA (cfDNA) in bodily fluids has rapidly transformed the development of
noninvasive prenatal testing, cancer liquid biopsy, and transplantation monitoring. Plasma …