Murine Fecal Microbiota Transplantation Alleviates Intestinal and Systemic Immune Responses in Campylobacter jejuni Infected Mice Harboring a Human Gut …

MM Heimesaat, K Mrazek, S Bereswill - Frontiers in Immunology, 2019 - frontiersin.org
Human campylobacteriosis constitutes a zoonotic food-borne disease and a progressively
rising health burden of significant socioeconomic impact. We have recently shown that …

Murine fecal microbiota transplantation lowers gastrointestinal pathogen loads and dampens pro-inflammatory immune responses in Campylobacter jejuni infected …

MM Heimesaat, K Mrazek, S Bereswill - Scientific Reports, 2019 - nature.com
Conventional mice are protected from Campylobacter jejuni infection by the murine host-
specific gut microbiota composition. We here addressed whether peroral fecal microbiota …

The Host-Specific Intestinal Microbiota Composition Impacts Campylobacter coli Infection in a Clinical Mouse Model of Campylobacteriosis

MM Heimesaat, C Genger, S Kløve, D Weschka… - Pathogens, 2020 - mdpi.com
Human Campylobacter-infections are progressively rising globally. However, the molecular
mechanisms underlying C. coli–host interactions are incompletely understood. In this study …

Intestinal Microbiota Shifts towards Elevated Commensal Escherichia coli Loads Abrogate Colonization Resistance against Campylobacter jejuni in Mice

LM Haag, A Fischer, B Otto, R Plickert, AA Kühl… - PloS one, 2012 - journals.plos.org
Background The zoonotic pathogen Campylobacter jejuni is a leading cause of bacterial
foodborne enterocolitis in humans worldwide. The understanding of immunopathology …

Can microbiota transplantation abrogate murine colonization resistance against Campylobacter jejuni ?

MM Heimesaat, R Plickert, A Fischer… - European Journal of …, 2013 - akjournals.com
Enterocolitis caused by Campylobacter jejuni represents an important socioeconomic
burden worldwide. The host-specific intestinal microbiota is essential for maintaining …

Fecal Microbiota Transplantation, Commensal Escherichia coli and Lactobacillus johnsonii Strains Differentially Restore Intestinal and Systemic Adaptive Immune …

I Ekmekciu, E Von Klitzing, C Neumann… - Frontiers in …, 2017 - frontiersin.org
The essential role of the intestinal microbiota in the well-functioning of host immunity
necessitates the investigation of species-specific impacts on this interplay. Aim of this study …

Novel Murine Infection Models Provide Deep Insights into the “Ménage à Trois” of Campylobacter jejuni, Microbiota and Host Innate Immunity

S Bereswill, A Fischer, R Plickert, LM Haag, B Otto… - PloS one, 2011 - journals.plos.org
Background Although Campylobacter jejuni-infections have a high prevalence worldwide
and represent a significant socioeconomic burden, it is still not well understood how C. jejuni …

Microbiota-derived metabolic factors reduce campylobacteriosis in mice

X Sun, K Winglee, RZ Gharaibeh, J Gauthier, Z He… - Gastroenterology, 2018 - Elsevier
Background & Aims Campylobacter jejuni, a prevalent foodborne bacterial pathogen,
exploits the host innate response to induce colitis. Little is known about the roles of …

Metabolomic signatures of intestinal colonization resistance against Campylobacter jejuni in mice

NW Shayya, R Bandick, LV Busmann… - Frontiers in …, 2023 - frontiersin.org
Introduction Campylobacter jejuni stands out as one of the leading causes of bacterial
enteritis. In contrast to humans, specific pathogen-free (SPF) laboratory mice display strict …

The intestinal microbiota influences Campylobacter jejuni colonization and extraintestinal dissemination in mice

JL O'Loughlin, DR Samuelson… - Applied and …, 2015 - Am Soc Microbiol
Campylobacter jejuni is a leading cause of human foodborne gastroenteritis worldwide. The
interactions between this pathogen and the intestinal microbiome within a host are of …