Multifaceted cellular pathways exhibit a crucial role in the preservation of homeostasis at the
molecular, cellular, and organism levels. One of the most important of these protective …

Acute kidney injury (AKI) is a common clinical syndrome that is related to high morbidity and
mortality. Oxidative stress, including the production of reactive oxygen species (ROS) …

Background: Renal disease is a serious health problem, with increasing incidence and
prevalence. Oxidative stress and inflammation play a key role in the pathogenesis and …

Chronic kidney disease (CKD) is one of the fastest-growing causes of death and is predicted
to become by 2040 the fifth global cause of death. CKD is characterized by increased …

Acute kidney injury is a devastating disease with high morbidity in hospitalized patients and
contributes to the pathogenesis of chronic kidney disease. An underlying mechanism of …

Redox is a constant phenomenon in organisms. From the signaling pathway transduction to
the oxidative stress during the inflammation and disease process, all are related to reduction …

Multifaceted cell defense pathways perform a critical role in the maintenance of homeostasis
at the cellular, tissue, and organism levels. The Keap1–Nrf2 pathway is one of the most …

Over 10% of the global population suffers from kidney disease. However, only kidney
replacement therapies, which burden medical expenses, are currently effective in treating …

Kidney disease affects~ 10% of the population worldwide, resulting in millions of deaths
each year. Mechanistically, oxidative stress is a major driver of various kidney diseases, and …

Oxidative stress is involved in acute kidney injury due to ischemia–reperfusion and
chemotherapy-induced nephrotoxicity. To investigate their basic mechanisms we studied the …