Summary The SARS-CoV-2 spike (S) protein variant D614G supplanted the ancestral virus
worldwide, reaching near fixation in a matter of months. Here we show that D614G was …

Virus genome sequence variants that appear over the course of an outbreak can be
exploited to map the trajectory of the virus from one susceptible host to another. While such …

The COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) infection has resulted in tremendous loss worldwide. Although viral spike (S) …

Abstract Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). The spike (S) protein that mediates SARS-CoV-2 …

SARS-CoV-2 spike (S) glycoprotein is the key target of current vaccine development efforts
to combat COVID-19; neutralizing antibodies bind S and interfere with S binding to its …

The emergence of SARS-CoV-2 has resulted in> 90,000 infections and> 3,000 deaths.
Coronavirus spike (S) glycoproteins promote entry into cells and are the main target of …

The spike protein (S-protein) of SARS-CoV-2, the protein that enables the virus to infect
human cells, is the basis for many vaccines and a hotspot of concerning virus evolution …

The SARS-CoV2 coronavirus responsible for the current COVID19 pandemic has been
reported to have a relatively low mutation rate. Nevertheless, a few prevalent variants have …

SARS-CoV-2 variants with spike (S)-protein D614G mutations now predominate globally.
We therefore compare the properties of the mutated S protein (SG614) with the original …

During the evolution of SARS-CoV-2 in humans a D614G substitution in the spike (S) protein
emerged and became the predominant circulating variant (S-614G) of the COVID-19 …