Plasma ceramides are associated with coronary atherosclerotic burden in patients with ST-segment elevation myocardial infarction

W Pan, L Li, M Sun, C Wang, S Fang, B Yu - International Journal of …, 2020 - Elsevier
Abstract Background Plasma ceramides (Cer), a subset of bioactive lipids, have mechanistic
links to atherosclerotic coronary artery disease (CAD) pathogenesis and are related to major …

Circulating ceramide: a new cardiometabolic biomarker in patients with comorbid acute coronary syndrome and type 2 diabetes mellitus

R Cao, Z Fang, S Li, M Xu, J Zhang, D Han… - Frontiers in …, 2020 - frontiersin.org
Aims This study investigated the association of circulating ceramides in patients with
comorbid acute coronary syndrome and type 2 diabetes mellitus (ACS-DM). Methods A total …

Plasma ceramides and cardiac risk

M Nicholls - European Heart Journal, 2017 - academic.oup.com
Developed by researchers at Mayo Clinic in the USA, the test measures blood
concentrations of plasma ceramides, a class of lipids that are highly linked to cardiovascular …

Could ceramides become the new cholesterol?

SA Summers - Cell metabolism, 2018 - cell.com
The Mayo Clinic recently introduced a diagnostic test that quantifies plasma ceramides in
order to identify patients at risk of major adverse cardiac events. By comparing recent …

Plasma ceramides predict cardiovascular death in patients with stable coronary artery disease and acute coronary syndromes beyond LDL-cholesterol

R Laaksonen, K Ekroos, M Sysi-Aho… - European heart …, 2016 - academic.oup.com
Aims The aim was to study the prognostic value of plasma ceramides (Cer) as
cardiovascular death (CV death) markers in three independent coronary artery disease …

Evaluation of plasma sphingolipids as mediators of the relationship between kidney disease and cardiovascular events

B Lidgard, N Bansal, LR Zelnick, AN Hoofnagle… - …, 2023 - thelancet.com
Background Sphingolipids are a family of circulating lipids with regulatory and signaling
roles that are strongly associated with both eGFR and cardiovascular disease. Patients with …

Plasma glucosylceramides and cardiovascular risk in incident hemodialysis patients

MM Mitsnefes, J Fitzpatrick, SM Sozio, BG Jaar… - Journal of clinical …, 2018 - Elsevier
Background Recent population-based studies identified plasma sphingolipids as
independent predictors of increased cardiovascular disease (CVD) morbidity and mortality …

Association between plasma ceramides and inducible myocardial ischemia in patients with established or suspected coronary artery disease undergoing myocardial …

A Mantovani, S Bonapace, G Lunardi, M Salgarello… - Metabolism, 2018 - Elsevier
Background Recent studies have suggested that specific plasma ceramides are
independently associated with major adverse cardiovascular events in patients with …

Fat-secreted ceramides regulate vascular redox state and influence outcomes in patients with cardiovascular disease

N Akawi, A Checa, AS Antonopoulos… - Journal of the American …, 2021 - jacc.org
Background Obesity is associated with increased cardiovascular risk; however, the potential
role of dysregulations in the adipose tissue (AT) metabolome is unknown. Objectives The …

Why and how increased plasma ceramides predict future cardiovascular events?

K Öörni, M Jauhiainen, PT Kovanen - Atherosclerosis, 2020 - atherosclerosis-journal.com
Plasma ceramides (CER), a class of sphingolipid molecules, have been identified as
markers of future cardiovascular (CV) events and measurement of certain ceramide species …