Long-and very long-chain ceramides are predictors of acute kidney injury in patients with acute coronary syndrome: the PEACP study

L Liang, D Li, R Zeng, H Zhang, L Lv, W Wei… - Cardiovascular …, 2023 - Springer
Background Acute kidney injury (AKI) can be caused by multiple factors/events, including
acute coronary syndrome (ACS). Ceramides are involved in atherosclerosis progression …

Associations of adiposity and diet quality with serum ceramides in middle-aged adults with cardiovascular risk factors

MA Drazba, I Holásková, NR Sahyoun… - Journal of Clinical …, 2019 - mdpi.com
Rates of adverse cardiovascular events have increased among middle-aged adults.
Elevated ceramides have been proposed as a risk factor for cardiovascular events. Diet …

Association between specific plasma ceramides and high-sensitivity C-reactive protein levels in postmenopausal women with type 2 diabetes

A Mantovani, A Altomari, G Lunardi, S Bonapace… - Diabetes & …, 2020 - Elsevier
Aim Emerging evidence suggests that specific plasma ceramides are involved in the
pathophysiology of cardiovascular disease (CVD) and other inflammation-associated …

[HTML][HTML] Plasma 16: 0 ceramide as a marker of cardiovascular risk estimated by carotid intima-media thickness in people with type 2 diabetes

D Denimal, L Duvillard, S Béland-Bonenfant… - Diabetes & …, 2024 - Elsevier
Aim New tools are required to better assess cardiovascular risk in individuals with type 2
diabetes mellitus (T2DM). Plasma ceramides emerge as promising candidates, given their …

Cardiovascular outcomes of patients in SAVOR-TIMI 53 by baseline hemoglobin A1c

MA Cavender, BM Scirica, I Raz, PG Steg… - The American journal of …, 2016 - Elsevier
Background The effect of saxagliptin on cardiovascular outcomes according to different
hemoglobin A1c (HbA1c) levels has not been described. Thus, we analyzed the SAVOR …

Sildenafil treatment in heart failure with preserved ejection fraction: targeted metabolomic profiling in the RELAX trial

H Wang, K Anstrom, O Ilkayeva, MJ Muehlbauer… - JAMA …, 2017 - jamanetwork.com
Importance Phosphodiesterase-5 inhibition with sildenafil compared with a placebo had no
effect on the exercise capacity or clinical status of patients with heart failure with preserved …

[HTML][HTML] Circulating ceramides as biomarkers of cardiovascular disease: Evidence from phenotypic and genomic studies

KA McGurk, BD Keavney, A Nicolaou - Atherosclerosis, 2021 - Elsevier
There is a need for new biomarkers of atherosclerotic cardiovascular disease (ACVD), the
main cause of death globally. Ceramides, a class of potent bioactive lipid mediators, have …

Insulin treatment increases myocardial ceramide accumulation and disrupts cardiometabolic function

AE Hodson, TS Tippetts, BT Bikman - Cardiovascular diabetology, 2015 - Springer
Background States of hyperinsulinemia, particularly insulin resistance and type 2 diabetes
mellitus, are becoming remarkably common, with roughly half a billion people likely to suffer …

Plasma levels of ceramides relate to ischemic stroke risk and clinical severity

Y Gui, Q Li, L Liu, P Zeng, RF Ren, ZF Guo… - Brain research …, 2020 - Elsevier
Recent studies have suggested that specific plasma ceramides are independently
associated with atherosclerosis and cardiovascular diseases, but it is currently unknown …

Association between sphingolipids and cardiopulmonary fitness in coronary artery disease patients undertaking cardiac rehabilitation

M Saleem, N Herrmann, A Dinoff… - The Journals of …, 2020 - academic.oup.com
The long-term benefits conferred by cardiac rehabilitation (CR) in those with coronary artery
disease (CAD) are strongly linked with an improvement in cardiopulmonary fitness. This …