Distinct severe acute respiratory syndrome coronavirus-induced acute lung injury pathways in two different nonhuman primate species
SL Smits, JMA van den Brand, A de Lang… - Journal of …, 2011 - Am Soc Microbiol
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS), caused by influenza
A virus H5N1 and severe acute respiratory syndrome coronavirus (SARS-CoV), supposedly …
A virus H5N1 and severe acute respiratory syndrome coronavirus (SARS-CoV), supposedly …
[HTML][HTML] Functional genomics highlights differential induction of antiviral pathways in the lungs of SARS-CoV–infected macaques
A De Lang, T Baas, T Teal, LM Leijten, B Rain… - PLoS …, 2007 - journals.plos.org
The pathogenesis of severe acute respiratory syndrome coronavirus (SARS-CoV) is likely
mediated by disproportional immune responses and the ability of the virus to circumvent …
mediated by disproportional immune responses and the ability of the virus to circumvent …
Mouse-passaged severe acute respiratory syndrome-associated coronavirus leads to lethal pulmonary edema and diffuse alveolar damage in adult but not young …
N Nagata, N Iwata, H Hasegawa, S Fukushi… - The American journal of …, 2008 - Elsevier
Advanced age is a risk factor of severe acute respiratory syndrome (SARS) in humans. To
understand its pathogenesis, we developed an animal model using BALB/c mice and the …
understand its pathogenesis, we developed an animal model using BALB/c mice and the …
Primary severe acute respiratory syndrome coronavirus infection limits replication but not lung inflammation upon homologous rechallenge
C Clay, N Donart, N Fomukong, JB Knight… - Journal of …, 2012 - Am Soc Microbiol
Our knowledge regarding immune-protective and immunopathogenic events in severe acute
respiratory syndrome coronavirus (SARS-CoV) infection is limited, and little is known about …
respiratory syndrome coronavirus (SARS-CoV) infection is limited, and little is known about …
Cytokine responses in severe acute respiratory syndrome coronavirus-infected macrophages in vitro: possible relevance to pathogenesis
CY Cheung, LLM Poon, IHY Ng, W Luk, SF Sia… - Journal of …, 2005 - Am Soc Microbiol
The pathogenesis of severe acute respiratory syndrome (SARS) remains unclear.
Macrophages are key sentinel cells in the respiratory system, and it is therefore relevant to …
Macrophages are key sentinel cells in the respiratory system, and it is therefore relevant to …
Mechanisms of host defense following severe acute respiratory syndrome-coronavirus (SARS-CoV) pulmonary infection of mice
WG Glass, K Subbarao, B Murphy… - The Journal of …, 2004 - journals.aai.org
We describe a model of severe acute respiratory syndrome-coronavirus (SARS-CoV)
infection in C57BL/6 mice. A clinical isolate of the virus introduced intranasally replicated …
infection in C57BL/6 mice. A clinical isolate of the virus introduced intranasally replicated …
Early upregulation of acute respiratory distress syndrome-associated cytokines promotes lethal disease in an aged-mouse model of severe acute respiratory …
B Rockx, T Baas, GA Zornetzer, B Haagmans… - Journal of …, 2009 - Am Soc Microbiol
Several respiratory viruses, including influenza virus and severe acute respiratory syndrome
coronavirus (SARS-CoV), produce more severe disease in the elderly, yet the molecular …
coronavirus (SARS-CoV), produce more severe disease in the elderly, yet the molecular …
Toll-like receptor 4 deficiency increases disease and mortality after mouse hepatitis virus type 1 infection of susceptible C3H mice
A Khanolkar, SM Hartwig, BA Haag… - Journal of …, 2009 - Am Soc Microbiol
Severe acute respiratory syndrome (SARS) is characterized by substantial acute pulmonary
inflammation with a high mortality rate. Despite the identification of SARS coronavirus …
inflammation with a high mortality rate. Despite the identification of SARS coronavirus …
[HTML][HTML] Viral pathogens and acute lung injury: investigations inspired by the SARS epidemic and the 2009 H1N1 influenza pandemic
CM Hendrickson, MA Matthay - Seminars in respiratory and …, 2013 - thieme-connect.com
Acute viral pneumonia is an important cause of acute lung injury (ALI), although not enough
is known about the exact incidence of viral infection in ALI. Polymerase chain reaction …
is known about the exact incidence of viral infection in ALI. Polymerase chain reaction …
SARS-CoV virus-host interactions and comparative etiologies of acute respiratory distress syndrome as determined by transcriptional and cytokine profiling of formalin …
T Baas, JK Taubenberger, PY Chong… - Journal of interferon & …, 2006 - liebertpub.com
These studies attempt to understand more fully the host response and pathogenesis
associated with severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) by …
associated with severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) by …
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