Atherosclerosis is characterized by chronic low grade inflammation of arteries that results in
the development of lipid dense plaques. Chronic inflammation induced by Western-type diet …

Macrophages are crucial in the progression of atherosclerotic cardiovascular disease
(ASCVD). In the atherosclerotic lesions, macrophages play a central role in maintaining …

After activation, cells of the myeloid lineage undergo robust metabolic transitions, as well as
discrete epigenetic changes, that can dictate both ongoing and future inflammatory …

Background and aims We have recently reported that monocytes can undergo functional
and transcriptional reprogramming towards a long-term pro-inflammatory phenotype after …

Low-grade systemic inflammation is a key pathophysiological component of atherosclerotic
cardiovascular disease (CVD), and long-term activation of myeloid cells is thought to be …

Atherosclerosis is the root cause of many cardiovascular diseases. Extensive research in
preclinical models and emerging evidence in humans have established the crucial roles of …

Atherosclerosis is characterized by incessant inflammation in the arterial wall in which
monocytes and macrophages play a crucial role. During the past few years, it has been …

Abstract Purpose of Review Atherosclerosis is an inflammatory disorder of the arterial wall,
in which several players contribute to the onset and progression of the disease. Besides the …

Macrophage immunometabolism, the changes in intracellular metabolic pathways that alter
the function of these highly plastic cells, has been the subject of intense interest in the past …

Atherosclerosis is an arterial disease process characterized by the focal subendothelial
accumulation of apolipoprotein-B-containing lipoproteins, immune and vascular wall cells …