COVID-19: immunohistochemical analysis of TGF-β signaling pathways in pulmonary fibrosis

CB Vaz de Paula, S Nagashima, V Liberalesso… - International journal of …, 2021 - mdpi.com
Acute respiratory distress syndrome (ARDS) followed by repair with lung remodeling is
observed in COVID-19. These findings can lead to pulmonary terminal fibrosis, a form of …

Discharge may not be the end of treatment: pay attention to pulmonary fibrosis caused by severe COVID‐19

C Zhang, Z Wu, JW Li, K Tan, W Yang… - Journal of medical …, 2021 - Wiley Online Library
Since December 2019, coronavirus disease (COVID‐19) has rapidly swept the world. So far,
more than 30 million people have been infected and nearly one million have died. Although …

[HTML][HTML] A potential treatment of COVID-19 with TGF-β blockade

WJ Chen - International Journal of Biological Sciences, 2020 - ncbi.nlm.nih.gov
The rapid spread of coronavirus SARS-CoV-2 causing COVID-19 across the world poses a
major threat to the global health. The major cause of death in infected patients is severe …

Pathophysiology of pulmonary fibrosis in the context of COVID-19 and implications for treatment: A narrative review

S Tran, A Ksajikian, J Overbey, P Li, Y Li - Cells, 2022 - mdpi.com
Pulmonary fibrosis (PF) is a feared outcome of many pulmonary diseases which results in a
reduction in lung compliance and capacity. The development of PF is relatively rare, but it …

COVID-19: the potential treatment of pulmonary fibrosis associated with SARS-CoV-2 infection

K Lechowicz, S Drożdżal, F Machaj, J Rosik… - Journal of clinical …, 2020 - mdpi.com
In December 2019, a novel coronavirus, SARS-CoV-2, appeared, causing a wide range of
symptoms, mainly respiratory infection. In March 2020, the World Health Organization …

COVID‐19 and pulmonary fibrosis: A potential role for lung epithelial cells and fibroblasts

AE John, C Joseph, G Jenkins… - Immunological reviews, 2021 - Wiley Online Library
The COVID‐19 pandemic rapidly spread around the world following the first reports in
Wuhan City, China in late 2019. The disease, caused by the novel SARS‐CoV‐2 virus, is …

[HTML][HTML] Pulmonary fibrosis in the aftermath of the COVID-19 era

E Vasarmidi, E Tsitoura… - Experimental …, 2020 - … .spandidos-publications.com
The year 2020 is characterized by the COVID‑19 pandemic that has resulted in more than
half a million deaths in recent months. The high mortality is associated with acute severe …

The interaction between pulmonary fibrosis and COVID-19 and the application of related anti-fibrotic drugs

H Shen, N Zhang, Y Liu, X Yang, Y He, Q Li… - Frontiers in …, 2022 - frontiersin.org
COVID-19 is a highly contagious respiratory disease, which mainly affects the lungs.
Critically ill patients are easily complicated by cytokine storms, acute respiratory distress …

Repurposing of histone deacetylase inhibitors: A promising strategy to combat pulmonary fibrosis promoted by TGF-β signalling in COVID-19 survivors

K Sivashanmugam, M Kandasamy, R Subbiah… - Life sciences, 2021 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) has rapidly spread around the world
causing global public health emergency. In the last twenty years, we have witnessed several …

IL-4/IL-13 remodeling pathway of COVID-19 lung injury

CB Vaz de Paula, MLV de Azevedo, S Nagashima… - Scientific Reports, 2020 - nature.com
The COVID-19 fatality rate is high when compared to the H1N1pdm09 (pandemic Influenza
A virus H1N1 subtype) rate, and although both cause an aggravated inflammatory response …