Various leptospiral components have been identified and shown to be involved in tissue
destruction. In addition, immune responses to leptospires have been implicated in target …

Leptospirosis remains one of the most widespread zoonotic diseases caused by spirochetes
of the genus Leptospira, which accounts for high morbidity and mortality globally …

Human leptospirosis is considered as one of the most widespread and potentially fatal
zoonotic diseases that causes high mortality and morbidity in the endemic regions of tropical …

Leptospirosis is a widespread zoonosis characterized by multiple organ failure and variable
host susceptibility toward pathogenic Leptospira strains. In this study, we put the role of …

Leptospirosis is a neglected tropical zoonosis caused by pathogenic spirochetes of the
genus Leptospira. Infected reservoir animals, typically mice and rats, are asymptomatic …

Leptospirosis is an emerging zoonosis caused by pathogenic spirochetes belonging to the
genus Leptospira. An understanding of leptospiral protein expression regulation is needed …

In order to quantify in vivo the mRNAs of cytokines which play important roles in
leptospirosis, we have developed quantitative real-time PCR assays for interleukin-2 (IL-2) …

Clinical manifestations of leptospirosis are highly variable: from asymptomatic to severe and
potentially fatal. The outcome of the disease is usually determined in the immunological …

Leptospirosis is an important zoonosis and has a worldwide impact on public health. This
paper will discuss both the role of immunogenic and pathogenic molecules during …

Background Leptospirosis is caused by pathogenic spirochetes of the genus Leptospira.
The bacteria enter the human body via abraded skin or mucous membranes and may …