Oximes have been studied for decades because of their significant roles as
acetylcholinesterase reactivators. Over the last twenty years, a large number of oximes have …

Oximes, which are highly bioactive molecules, have versatile uses in the medical sector and
have been indicated to possess biological activity. Certain oximes exist in nature in plants …

Despite the scientific advancements, organophosphate (OP) poisoning continues to be a
major threat to humans, accounting for nearly one million poisoning cases every year …

Small-molecule kinase inhibitors are being continuously explored as new anticancer
therapeutics. Kinases are the phosphorylating enzymes which regulate numerous cellular …

Oxindole has been shown to be a pharmacologically advantageous scaffold having many
biological properties that are relevant to medicinal chemistry. The simplicity and widespread …

Nonsteroidal antiinflammatory drugs (NSAIDs) have chemopreventive effects in several
cancer types, and the oxicam-based NSAIDs meloxicam and piroxicam exhibit potential to …

Oxindoles are credited to have a wide range of applications and are reported to exhibit an
extensive range of biological effects which include the antiviral, antifungal, antibacterial …

Background: Steroids play an important role in life because they can regulate a variety of
biological processes and have been widely used in medicine namely as antiinflammatory …

Leukotrienes are the bioactive group of fatty acids and major constituents of arachidonic
acid metabolism molded by the catalytic activity of 5-lipoxygenase (5-LOX). Evidence is …

The products of arachidonic acid metabolism by lipoxygenase (LOX) and cyclooxygenase
(COX) significantly contribute to inflammation and carcinogenesis. Particularly …