Objective The Consortium on the Genetics of Schizophrenia has undertaken a large
multisite study to characterize 12 neurophysiological and neurocognitive endophenotypic …

Objective: The authors used a custom array of 1,536 single-nucleotide polymorphisms
(SNPs) to interrogate 94 functionally relevant candidate genes for schizophrenia and identify …

Background Although many endophenotypes for schizophrenia have been studied
individually, few studies have examined the extent to which common neurocognitive and …

Background: Twin and multiplex family studies have established significant heritability for
schizophrenia (SZ), often summarized as 81%. The Consortium on the Genetics of …

The genetics of schizophrenia has been approached utilizing a variety of methods. One
emerging strategy is the use of endophenotypes in order to understand and identify the …

The search for the genetic architecture of schizophrenia has employed multiple, often
converging strategies. One such strategy entails the use of tracing the heritability and …

Abstract The Consortium on the Genetics of Schizophrenia (COGS) is a 7-site collaboration
that examines the genetic architecture of quantitative endophenotypes in families with …

Schizophrenia is an idiopathic mental disorder with a heritable component and a substantial
public health impact. We conducted a multi-stage genome-wide association study (GWAS) …

While it is clear that schizophrenia is highly heritable, the genetic basis of this heritability is
complex. Human genetic, brain imaging, and model organism studies have met with only …

Context Exploration of the genetic architecture of specific endophenotypes may be a
powerful strategy for understanding the genetic basis of schizophrenia. Objective To …