Importance Schizophrenia (SCZ) is a devastating psychiatric condition. Identifying the
specific genetic variants and pathways that increase susceptibility to SCZ is critical to …

Schizophrenia (SCZ) is a complex and heterogeneous mental disorder that affects about 1%
of global population. In recent years, considerable progress has been made in genetic …

Schizophrenia (SZ) is a debilitating brain disorder with a complex genetic architecture.
Genetic studies, especially recent genome-wide association studies (GWAS), have identified …

Abstract Purpose of Review This is an era where we have significantly advanced the
understanding of the genetic architecture of schizophrenia. In this review, we consider how …

Over the last 8 years the Psychiatric Genomics Consortium (PGC; http://pgc. unc. edu) has
fundamentally changed the landscape for psychiatric genetics research. This has been …

Schizophrenia is a severe psychiatric disorder with strong heritability and marked
heterogeneity in symptoms, course, and treatment response. There is strong interest in …

Abstract The Psychiatric Genomics Consortium–Schizophrenia Workgroup (PGC–SCZ) has
recently published a genomewide association study (GWAS) identifying> 100 genetic loci …

Background Therapeutic treatments for schizophrenia do not alleviate symptoms for all
patients and efficacy is limited by common, often severe, side-effects. Genetic studies of …

Little is known for certain about the genetics of schizophrenia. The advent of genomewide
association has been widely anticipated as a promising means to identify reproducible DNA …

BackgroundCandidate gene studies have been a key approach to the genetics of
schizophrenia (SCZ). However, the results of these studies are confusing and no genes …