A Patel, JA Chad, JJ Chen - Obesity, 2023 - Wiley Online Library
Objective The role of vascular risk factors in age‐related brain degeneration has long been the subject of intense study, but the role of obesity remains understudied. Given known sex …
Z Zhang, X Chen, Z Sheng - Scientific Reports, 2024 - nature.com
The relationship between the triglyceride glucose-body mass index (TyG-BMI) index and Alzheimer's disease (AD) pathology, cognition, and brain structure remains unclear. This …
K Moazzami, MC Power, R Gottesman, T Mosley… - Neuroimage, 2020 - Elsevier
Background Limited information exists regarding the association between midlife lipid levels and late-life total and regional brain volumes. Methods We studied 1872 participants in the …
V Isaac, S Sim, H Zheng, V Zagorodnov… - Frontiers in aging …, 2011 - frontiersin.org
The link between central adiposity and cognition has been established by indirect measures such as body mass index (BMI) or waist–hip ratio. Magnetic resonance imaging (MRI) …
Introduction Cardio-metabolic risk factors have been associated with poor physical and mental health. Epidemiological studies have shown peripheral risk markers to be associated …
Aside from cortical damage associated with age, cerebrovascular and neurodegenerative diseases, it's an outstanding question if factors of global health, including normal variation in …
Chronic obesity is associated with several complications, including cognitive impairment and dementia. However, we have piecemeal knowledge of the mechanisms linking obesity …
Background Identifying blood-based signatures of brain health and preclinical pathology may offer insights into early disease mechanisms and highlight avenues for intervention …
Objectives: Obesity and dyslipidemia may be associated with hippocampal alterations and may increase the risk of neurodegeneration. This study studied hippocampal anatomical …