The structure and integrity of the ageing brain is interchangeably linked to physical health,
and cardiometabolic risk factors (CMRs) are associated with dementia and other brain …

Objective Recently, the lipid profile of atherogenic dyslipidemia has become important in
cerebrovascular diseases. Atherogenic index of plasma (AIP), an index that reflects this lipid …

To establish causal evidence for the association of adiposity-related metabolic abnormalities
with brain volumes, and the risks of dementia and stroke, we applied 1-and 2-sample …

Objective: Vascular risk factors like hyperlipidemia may adversely affect brain function. We
hypothesized that increased serum triglycerides are associated with decreased executive …

Our knowledge of the mechanisms underlying the vulnerability of the brain's white matter
microstructure to cardiovascular risk factors (CVRFs) is still limited. We used a quantitative …

Healthy cognitive ageing is a societal and public health priority. Cerebrovascular risk factors
increase the likelihood of dementia in older people but their impact on cognitive ageing in …

Aging affects brain structure and function alongside metabolic and vascular processes
leading to energetic impairments. While local neurometabolic dysfunction in aging is well …

Objective Adiposity predictors, body mass index (BMI), waist circumference (WC), and blood
leptin and total adiponectin levels were associated with components of cerebral small vessel …

Objective: To explore causal associations between BMI-independent body fat distribution
profiles and cerebrovascular disease risk, and to investigate potential mediators underlying …

Objective To investigate the association of triglyceride (TG) principal component scores with
Alzheimer disease (AD) and the amyloid, tau, neurodegeneration, and cerebrovascular …