Plasma lipids and cerebral small vessel disease

S Schilling, C Tzourio, C Dufouil, Y Zhu, C Berr… - Neurology, 2014 - AAN Enterprises
Objectives: We examined the cross-sectional association between lipid fractions and 2 MRI
markers of cerebral small vessel disease, white matter hyperintensity volume (WMHV) and …

Relations of metabolic health and obesity to brain aging in young to middle‐aged adults

R Angoff, JJ Himali, P Maillard, HJ Aparicio… - Journal of the …, 2022 - Am Heart Assoc
Background We aimed to evaluate the association between metabolic health and obesity
and brain health measured via magnetic resonance imaging and neurocognitive testing in …

Revealing a novel landscape of the association between blood lipid levels and Alzheimer's disease: a meta-analysis of a case-control study

Q Tang, F Wang, J Yang, H Peng, Y Li, B Li… - Frontiers in Aging …, 2020 - frontiersin.org
Objectives: Blood lipid profiles have been ambiguously reported as biomarkers of AD in
recent years. This study was conducted to evaluate the correlation between blood lipid …

Lipid metabolism in the development and progression of vascular cognitive impairment: a systematic review

Q Qin, Y Yin, Y Xing, X Wang, Y Wang, F Wang… - Frontiers in …, 2021 - frontiersin.org
Background: Vascular cognitive impairment (VCI) is a major public health problem. The
current diagnosis of VCI is made based on the assessment of clinical symptoms and …

Associations between cardiometabolic multimorbidity and cerebrospinal fluid biomarkers of Alzheimer's disease pathology in cognitively intact adults: the CABLE …

QY Li, HY Hu, GW Zhang, H Hu, YN Ou… - Alzheimer's Research & …, 2024 - Springer
Background Cardiometabolic multimorbidity is associated with an increased risk of
dementia, but the pathogenic mechanisms linking them remain largely undefined. We aimed …

Higher Dietary Inflammatory Index scores are associated with brain MRI markers of brain aging: Results from the Framingham Heart Study Offspring cohort

D Melo Van Lent, H Gokingco, MI Short… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction We investigated cross‐sectional associations between the Dietary Inflammatory
Index (DII) and measures of brain volume and cerebral small vessel disease among …

Abdominal fat depots are related to lower cognitive functioning and brain volumes in middle‐aged males at high Alzheimer's risk

S Golan Shekhtman, E Boccara, R Ravona‐Springer… - …, 2024 - Wiley Online Library
Objective High BMI, which poorly represents specific fat depots, is linked to poorer cognition
and higher dementia risk, with different associations between sexes. This study examined …

[HTML][HTML] Body fat and components of sarcopenia relate to inflammation, brain volume, and neurometabolism in older adults

WAJ Vints, S Kušleikienė, S Sheoran… - Neurobiology of …, 2023 - Elsevier
Obesity and sarcopenia are associated with cognitive impairments at older age. Current
research suggests that blood biomarkers may mediate this body-brain crosstalk, altering …

The Relationships Between Lipid Accumulation Product Levels and Cognitive Decline Over 4 Years in a Rural Area of Xi'an, China

Y Wang, S Wei, R Zhou, S Shang, L Dang… - Frontiers in Aging …, 2021 - frontiersin.org
Background and Aims: The relationships between blood lipid levels and obesity and
cognitive impairment have not been fully determined. Considering that the lipid …

Associations of brain structure with adiposity and changes in adiposity in a middle-aged and older biracial population

BG Windham, ST Lirette, M Fornage… - … Series A: Biomedical …, 2017 - academic.oup.com
Background: Studies of adiposity and brain pathology in African Americans (AA) are sparse
despite higher rates of obesity, dementia, and dementia-associated brain pathology in AA …