Mass spectrometry‐based proteomic platforms for better understanding of SARS‐CoV‐2 induced pathogenesis and potential diagnostic approaches

N Ahsan, RSP Rao, RS Wilson, U Punyamurtula… - …, 2021 - Wiley Online Library
While protein–protein interaction is the first step of the SARS‐CoV‐2 infection, recent
comparative proteomic profiling enabled the identification of over 11,000 protein dynamics …

Plasma proteome fingerprints reveal distinctiveness and clinical outcome of SARS-CoV-2 infection

W Bauer, M Weber, E Diehl-Wiesenecker, N Galtung… - Viruses, 2021 - mdpi.com
Background: We evaluated how plasma proteomic signatures in patients with suspected
COVID-19 can unravel the pathophysiology, and determine kinetics and clinical outcome of …

Proteomics and machine learning approaches reveal a set of prognostic markers for COVID-19 severity with drug repurposing potential

K Suvarna, D Biswas, MGJ Pai, A Acharjee… - Frontiers in …, 2021 - frontiersin.org
The pestilential pathogen SARS-CoV-2 has led to a seemingly ceaseless pandemic of
COVID-19. The healthcare sector is under a tremendous burden, thus necessitating the …

Proteomics-based insights into the SARS-CoV-2–mediated COVID-19 pandemic: a review of the first year of research

JL Praissman, L Wells - Molecular & Cellular Proteomics, 2021 - ASBMB
In late 2019, a virus subsequently named severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) emerged in China and led to a worldwide pandemic of the disease termed …

Longitudinal plasma proteomic analysis of 1117 hospitalized patients with COVID-19 identifies features associated with severity and outcomes

A Viode, KK Smolen, P van Zalm, D Stevenson… - Science …, 2024 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is characterized
by highly heterogeneous manifestations ranging from asymptomatic cases to death for still …

In-depth blood proteome profiling analysis revealed distinct functional characteristics of plasma proteins between severe and non-severe COVID-19 patients

J Park, H Kim, SY Kim, Y Kim, JS Lee, K Dan… - Scientific reports, 2020 - nature.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over forty
million patients worldwide. Although most coronavirus disease 2019 (COVID-19) patients …

Plasma proteomics identify potential severity biomarkers from COVID‐19 associated network

AT Sahin, A Yurtseven, S Dadmand… - PROTEOMICS …, 2023 - Wiley Online Library
Abstract Purpose Coronavirus disease 2019 (COVID‐19) continues to threaten public health
globally. Severe acute respiratory coronavirus type 2 (SARS‐CoV‐2) infection‐dependent …

Identification and validation of predictive factors for progression to severe COVID-19 pneumonia by proteomics

B Di, H Jia, OJ Luo, F Lin, K Li, Y Zhang… - Signal transduction and …, 2020 - nature.com
Recent study showed that around 80% of coronavirus disease-19 (COVID-19) patients are
moderate cases who will recover with or without conventional treatment, while the remaining …

Next generation plasma proteome profiling of COVID-19 patients with mild to moderate symptoms

W Zhong, O Altay, M Arif, F Edfors, L Doganay… - …, 2021 - thelancet.com
Background COVID-19 has caused millions of deaths globally, yet the cellular mechanisms
underlying the various effects of the disease remain poorly understood. Recently, a new …

CoVProt: Toward a Mass Spectrometry Data Portal for COVID-19 Proteomics Research and Development

S Rajoria, SR Kavuru, HS Pyda, S Bihani… - OMICS: A Journal of …, 2024 - liebertpub.com
The coronavirus disease 2019 (COVID-19) pandemic has wreaked havoc globally. Beyond
the pandemic, the long-term effects of the severe acute respiratory syndrome coronavirus 2 …