Complex changes in serum protein levels in COVID-19 convalescents

S Pushalkar, S Wu, S Maity, M Pressler… - Scientific Reports, 2024 - nature.com
The COVID-19 pandemic, triggered by severe acute respiratory syndrome coronavirus 2,
has affected millions of people worldwide. Much research has been dedicated to our …

Prognostic tools and candidate drugs based on plasma proteomics of patients with severe COVID-19 complications

MAY Al-Nesf, HB Abdesselem, I Bensmail… - Nature …, 2022 - nature.com
COVID-19 complications still present a huge burden on healthcare systems and warrant
predictive risk models to triage patients and inform early intervention. Here, we profile 893 …

A time-resolved proteomic and prognostic map of COVID-19

V Demichev, P Tober-Lau, O Lemke, T Nazarenko… - Cell systems, 2021 - cell.com
COVID-19 is highly variable in its clinical presentation, ranging from asymptomatic infection
to severe organ damage and death. We characterized the time-dependent progression of …

Plasma proteomics unveil novel immune signatures and biomarkers upon SARS-CoV-2 infection

V Urbiola-Salvador, S Lima de Souza… - International Journal of …, 2023 - mdpi.com
Several elements have an impact on COVID-19, including comorbidities, age and sex. To
determine the protein profile changes in peripheral blood caused by a SARS-CoV-2 …

Plasma proteomic variables related to COVID-19 severity: an untargeted nLC-MS/MS investigation

L Pagani, C Chinello, G Risca, G Capitoli… - International Journal of …, 2023 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection leads to a wide
range of clinical manifestations and determines the need for personalized and precision …

COVID‐19 plasma proteome reveals novel temporal and cell‐specific signatures for disease severity and high‐precision disease management

C Iosef, CM Martin, M Slessarev… - Journal of Cellular …, 2023 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is a systemic inflammatory condition with
high mortality that may benefit from personalized medicine and high‐precision approaches …

Plasma proteomic signature predicts who will get persistent symptoms following SARS-CoV-2 infection

G Captur, JC Moon, CC Topriceanu, G Joy… - …, 2022 - thelancet.com
Background The majority of those infected by ancestral Severe Acute Respiratory Syndrome
Coronavirus 2 (SARS-CoV-2) during the UK first wave (starting March 2020) did not require …

Proteomic approaches to study SARS-CoV-2 biology and COVID-19 pathology

P Haas, M Muralidharan, NJ Krogan… - Journal of proteome …, 2021 - ACS Publications
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative
agent of coronavirus disease 2019 (COVID-19), was declared a pandemic infection in March …

COVIDpro: Database for mining protein dysregulation in patients with COVID-19

F Zhang, A Luna, T Tan, Y Chen… - Journal of Proteome …, 2023 - ACS Publications
The ongoing pandemic of the coronavirus disease 2019 (COVID-19) caused by the severe
acute respiratory syndrome coronavirus 2 still has limited treatment options. Our …

Characterization by quantitative serum proteomics of immune-related prognostic biomarkers for COVID-19 symptomatology

M Villar, JM Urra, FJ Rodríguez-del-Río… - Frontiers in …, 2021 - frontiersin.org
The COVID-19 pandemic caused by SARS-CoV-2 challenges the understanding of factors
affecting disease progression and severity. The identification of prognostic biomarkers and …