Mass spectrometry-based proteomics in basic and translational research of SARS-CoV-2 coronavirus and its emerging mutants

Y Rais, Z Fu, AP Drabovich - Clinical Proteomics, 2021 - Springer
Molecular diagnostics of the coronavirus disease of 2019 (COVID-19) now mainly relies on
the measurements of viral RNA by RT-PCR, or detection of anti-viral antibodies by …

Proteotyping SARS-CoV-2 virus from nasopharyngeal swabs: a proof-of-concept focused on a 3 min mass spectrometry window

D Gouveia, G Miotello, F Gallais… - Journal of Proteome …, 2020 - ACS Publications
Rapid but yet sensitive, specific, and high-throughput detection of the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) in clinical samples is key to diagnose …

Proteomics analysis of serum from COVID-19 patients

X Liu, Y Cao, H Fu, J Wei, J Chen, J Hu, B Liu - ACS omega, 2021 - ACS Publications
Coronavirus disease 2019 (COVID-19) is a worldwide pandemic. To understand the
changes in plasma proteomics upon SARS-CoV-2 infection, we analyzed the protein profiles …

Organ and cell-specific biomarkers of Long-COVID identified with targeted proteomics and machine learning

MA Patel, MJ Knauer, M Nicholson, M Daley… - Molecular …, 2023 - Springer
Background Survivors of acute COVID-19 often suffer prolonged, diffuse symptoms post-
infection, referred to as “Long-COVID”. A lack of Long-COVID biomarkers and …

Metabolic snapshot of plasma samples reveals new pathways implicated in SARS-CoV-2 pathogenesis

OE Albóniga, D Jiménez… - Journal of Proteome …, 2022 - ACS Publications
Despite the scientific and human efforts to understand COVID-19, there are questions still
unanswered. Variations in the metabolic reaction to SARS-CoV-2 infection could explain the …

[HTML][HTML] Re-analysis of SARS-CoV-2-infected host cell proteomics time-course data by impact pathway analysis and network analysis: a potential link with …

JO Bock, I Ortea - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19), caused by an outbreak of the severe acute
respiratory syndrome-coronavirus 2 (SARS-CoV-2) in Wuhan, China, has led to an …

A bioinformatics approach to mine the microbial proteomic profile of COVID-19 mass spectrometry data

AAA Alnakli, A Jabeen, R Chakraborty… - Applied …, 2022 - mdpi.com
Mass spectrometry (MS) is one of the key technologies used in proteomics. The majority of
studies carried out using proteomics have focused on identifying proteins in biological …

Plasma Proteome‐Wide Mendelian Randomization Analysis Reveals Biomarkers and Therapeutic Targets for Different Stages of COVID‐19

S Krishnamoorthy, RLC Hoo… - … and Emerging Diseases, 2024 - Wiley Online Library
Background. The COVID‐19 pandemic caused by the SARS‐CoV‐2 virus has resulted in a
global health crisis with significant morbidity and mortality. While effective vaccinations have …

Proteomics and its application in pandemic diseases

SS Thakur - Journal of Proteome Research, 2020 - ACS Publications
Pandemics create havoc in human life and are not simply old-world problems. A series of
recent viral outbreaks including HIV, influenza, Ebola, Zika, and SARS-CoV-2 have elevated …

Role of multiomics data to understand host–pathogen interactions in COVID-19 pathogenesis

S Aggarwal, A Acharjee, A Mukherjee… - Journal of Proteome …, 2021 - ACS Publications
Human infectious diseases are contributed equally by the host immune system's efficiency
and any pathogens' infectivity. Severe acute respiratory syndrome coronavirus 2 (SARS …