Long-term outdoor air pollution and DNA methylation in circulating monocytes: results from the Multi-Ethnic Study of Atherosclerosis (MESA)

GC Chi, Y Liu, JW MacDonald, RG Barr… - Environmental …, 2016 - Springer
Background DNA methylation may mediate effects of air pollution on cardiovascular
disease. The association between long-term air pollution exposure and DNA methylation in …

Epigenome-wide analysis of long-term air pollution exposure and DNA methylation in monocytes: results from the Multi-Ethnic Study of Atherosclerosis

GC Chi, Y Liu, JW MacDonald, LM Reynolds… - Epigenetics, 2022 - Taylor & Francis
Air pollution might affect atherosclerosis through DNA methylation changes in cells crucial to
atherosclerosis, such as monocytes. We conducted an epigenome-wide study of DNA …

DNA hypomethylation and its mediation in the effects of fine particulate air pollution on cardiovascular biomarkers: a randomized crossover trial

R Chen, X Meng, A Zhao, C Wang, C Yang, H Li… - Environment …, 2016 - Elsevier
Background Short-term exposure to fine particulate matter (PM 2.5) air pollution has been
associated with altered DNA methylation in observational studies, but it remains unclear …

[HTML][HTML] Methylome-wide association study provides evidence of particulate matter air pollution-associated DNA methylation

R Gondalia, A Baldassari, KM Holliday… - Environment …, 2019 - Elsevier
Background DNA methylation (DNAm) may contribute to processes that underlie
associations between air pollution and poor health. Therefore, our objective was to evaluate …

Gaseous air pollutants and DNA methylation in a methylome-wide association study of an ethnically and environmentally diverse population of US adults

KM Holliday, R Gondalia, A Baldassari, AE Justice… - Environmental …, 2022 - Elsevier
Epigenetic mechanisms may underlie air pollution-health outcome associations. We
estimated gaseous air pollutant-DNA methylation (DNAm) associations using twelve …

Long-term ambient fine particulate matter and DNA methylation in inflammation pathways: results from the Sister Study

C Wang, KM O'Brien, Z Xu, DP Sandler, JA Taylor… - Epigenetics, 2020 - Taylor & Francis
Although underlying mechanisms of long-term exposure to air pollution and cardiovascular
disease remain obscure, effects might partially act through changes in DNA methylation. We …

Genome-wide analysis of DNA methylation and fine particulate matter air pollution in three study populations: KORA F3, KORA F4, and the normative aging study

T Panni, AJ Mehta, JD Schwartz… - Environmental …, 2016 - ehp.niehs.nih.gov
Background: Epidemiological studies have reported associations between particulate matter
(PM) concentrations and cancer and respiratory and cardiovascular diseases. DNA …

Rapid DNA methylation changes after exposure to traffic particles

A Baccarelli, RO Wright, V Bollati… - American journal of …, 2009 - atsjournals.org
Rationale: Exposure to particulate air pollution has been related to increased hospitalization
and death, particularly from cardiovascular disease. Lower blood DNA methylation content …

Genome-wide DNA methylation and long-term ambient air pollution exposure in Korean adults

MK Lee, CJ Xu, MU Carnes, CE Nichols, JM Ward… - Clinical …, 2019 - Springer
Background Ambient air pollution is associated with numerous adverse health outcomes,
but the underlying mechanisms are not well understood; epigenetic effects including altered …

Prolonged exposure to particulate pollution, genes associated with glutathione pathways, and DNA methylation in a cohort of older men

J Madrigano, A Baccarelli, MA Mittleman… - Environmental …, 2011 - ehp.niehs.nih.gov
Background: DNA methylation is a potential pathway linking environmental exposures to
disease. Exposure to particulate air pollution has been associated with increased …