Safe and purposeful genome editing under harmonized regulation for responsible use: views of research experts

PD Ramos, MS Almeida, IAS Olsson - New Genetics and Society, 2023 - Taylor & Francis
CRISPR-Cas9 revolutionized the precise editing of mammalian cells genome. The present
study explores genome editing (GE) in the context of the Responsible Research and …

Political, Regulatory and Ethical Considerations of the CRISPR/Cas Genome Editing Technology

ER Yunta, LM Vaschetto - CRISPR-/Cas9 Based Genome Editing …, 2022 - taylorfrancis.com
This chapter reviews political, regulatory and ethical issues related to the implementation of
the CRISPR-Cas technology for genome editing in human cells. Regulations in the United …

Beyond safety: mapping the ethical debate on heritable genome editing interventions

M Almeida, R Ranisch - Humanities and Social Sciences …, 2022 - nature.com
Genetic engineering has provided humans the ability to transform organisms by direct
manipulation of genomes within a broad range of applications including agriculture (eg, GM …

[HTML][HTML] Focus: genome editing: gene editing in humans: towards a global and inclusive debate for responsible research

I De Lecuona, M Casado, G Marfany… - The Yale Journal of …, 2017 - ncbi.nlm.nih.gov
Abstract In December 2016, the Opinion Group of the Bioethics and Law Observatory (OBD)
of the University of Barcelona launched a Declaration on Bioethics and Gene Editing in …

Gene editing using CRISPR/Cas9: implications for dual-use and biosecurity

D DiEuliis, J Giordano - Protein & cell, 2018 - academic.oup.com
We have read with interest the recent paper by Kang, et al (2017), addressing clinical and
ethical issues related to the safe and responsible use of CRISPR/Cas. The authors provide a …

As CRISPR–Cas adoption soars, summit calls for genome editing oversight

S Jasanoff - Nature biotechnology, 2018 - nature.com
Researchers are using a pair of initiatives, launched within a few days of each other, to
widen the discussion about genome editing oversight to include countries often excluded …

themed issue: understanding the technical and social landscape of gene editing

R Dimond, J Lewis, G Thomas - New Genetics and Society, 2021 - Taylor & Francis
If we were to look ahead, perhaps with a wistful view to what we think would be interesting to
read about, the expanded availability, over the past two or three years, of gene editing …

Public and stakeholder engagement in developing human heritable genome editing policies: what does it mean and what should it mean?

AS Iltis, S Hoover, KRW Matthews - Frontiers in Political Science, 2021 - frontiersin.org
As scientific research pushes the boundaries of knowledge, new discoveries and
technologies often raise ethical and social questions. Public responses vary from surprise, to …

[PDF][PDF] HERITABLE HUMAN GENOME EDITING

RL Jugarap, F Edillo - researchgate.net
Since the discovery of CRISPR-Cas9 technology in 2012 by Nobel prize winner Jennifer
Doudna and Emmanuelle Charpentier, approaches for performing precise and targeted …

“O brave new world” CRISPR Mediated Gene Editing in Somatic and Germ Line Contexts for Therapeutics and Enhancement of the Human Species–an Ethical and …

CB Farrell - 2016 - repository.rcsi.com
Gene editing has been a topic of controversy since the late 1970's, however as of 2015 the
topic of gene editing and its potential applications has shot to the forefront of biomedical …