Microbiota and lung cancer. opportunities and challenges for improving immunotherapy efficacy

M Ocáriz-Díez, M Cruellas, M Gascón, R Lastra… - Frontiers in …, 2020 - frontiersin.org
The advances in molecular biology and the emergence of Next Generation Sequencing
(NGS) have revealed that microbiome composition is closely related with health and …

The lung microbiota and lung cancer: a growing relationship

M Bou Zerdan, J Kassab, P Meouchy, E Haroun… - Cancers, 2022 - mdpi.com
Simple Summary In the past few years, the microbiota has emerged as a major player in
cancer management. The efficacy of chemotherapy or immunotherapy may be influenced by …

[HTML][HTML] The influence of lung microbiota on lung carcinogenesis, immunity, and immunotherapy

AG Ramírez-Labrada, D Isla, A Artal, M Arias… - Trends in cancer, 2020 - cell.com
Microbiota have emerged as key modulators of both the carcinogenic process and the
immune response against cancer cells, and, thus, it seems to influence the efficacy of …

Lung microbiome: An emerging player in lung cancer pathogenesis and progression

A Karvela, OZ Veloudiou, A Karachaliou… - Clinical and …, 2023 - Springer
The microbiome of the lungs, although until recently neglected, is now emerging as a
potential contributor to chronic lung diseases, including cancer. Preclinical evidence …

Lung and gut microbiota as potential hidden driver of immunotherapy efficacy in lung cancer

C Carbone, G Piro, V Di Noia… - Mediators of …, 2019 - Wiley Online Library
Lung cancer is one of the deadliest and most common malignancies in the world,
representing one of the greatest challenges in cancer treatment. Immunotherapy is rapidly …

The lung microbiome in carcinogenesis and immunotherapy treatment

K Kennedy, K Khaddour, N Ramnath… - The Cancer …, 2023 - journals.lww.com
Lung cancer is the leading cause of cancer-related deaths. Over the past 10 years,
significant advances in treatment modalities, including immune checkpoint inhibitor (ICI) …

The role of the microbiome in cancer and therapy efficacy: focus on lung cancer

A Halley, A Leonetti, A Gregori, M Tiseo… - Anticancer …, 2020 - ar.iiarjournals.org
The microbiome is extremely important for human health; more recently its role in the context
of cancer became clear. Microbial effects range from enhancing cancer immunity and cancer …

Microbiome: a supportive or a leading actor in lung cancer?

D Martins, F Mendes, F Schmitt - Pathobiology, 2021 - karger.com
Lung cancer is still the leading cause of cancer death worldwide. Despite the major
diagnostic and therapeutic innovations, the effect on mortality has been modest and the …

Exploring the role of respiratory microbiome in lung cancer: A systematic review

F Perrone, L Belluomini, M Mazzotta, M Bianconi… - Critical Reviews in …, 2021 - Elsevier
Giving the potential contribute in cancer initiation and progression, lung microbiota
represents a promising topic in cancer research, although still unexplored. We performed a …

The lung, the niche, and the microbe: Exploring the lung microbiome in cancer and immunity

M Huynh, MJ Crane, AM Jamieson - Frontiers in Immunology, 2023 - frontiersin.org
The lung is a complex and unique organ system whose biology is strongly influenced by
environmental exposure, oxygen abundance, connection to extrapulmonary systems via a …