An amphiphilic polymer-drug conjugate was prepared by attachment of low molecular
weight methoxy poly (ethylene glycol)(PEG)(ie, 2 kDa) to docetaxel (DTX) through an ester …

Docetaxel (DTX), a chemotherapeutic agent, was coupled to the hydrophobic block of poly
(ethylene glycol)-b-poly (ε-caprolactone)(PEG-b-PCL) copolymers synthesized by metal free …

The oral delivery of docetaxel (DTX) is challenging due to a low bioavailability, related to an
important pre-systemic metabolism. With the aim of improving the bioavailability of this …

The purpose of this study is to synthesis and evaluate the antitumor efficacy of a novel
carboxymethyl chitosan–docetaxel (CMCS–DTX) conjugates and the availability of CMCS …

Due to the high frequency and mortality of breast cancer, developing efficient targeted drug
delivery systems for frightening against this malignancy is among cancer research priorities …

Docetaxel (DTX) can produce anti-tumor effects by inhibiting cell growth and inducing
apoptosis. However, the poor solubility of DTX restricts its application and its clinical …

The purpose of this study is to evaluate in vivo antitumor efficacy and subacute toxicity of
docetaxel (DTX) prodrug comprising a conjugate between DTX and low molecular weight …

A nanoparticle formulation of docetaxel (DTX) was designed to address the strengths and
limitations of current taxane delivery systems: PEGylation, high drug conjugation efficiency …

In this paper we describe the synthesis, physicochemical characteristics and data on the
biological activity of polymer prodrugs based on the anticancer drugs paclitaxel (PTX) and …

Docetaxel (DTX) has been widely used for the treatment of many types of cancer. However,
DTX is poorly water-soluble and commercial DTX is formulated in non-ionic surfactant …