[HTML][HTML] Genetic polymorphisms in ADRB1, ADRB2 and CYP2D6 genes and response to beta-blockers in patients with acute coronary syndrome

C Castaño-Amores, A Antúnez-Rodríguez… - Biomedicine & …, 2023 - Elsevier
Betablockers (BBs) are prescribed for ischaemia in patients with acute coronary syndrome
(ACS). In Spain, bisoprolol and carvedilol are the most prescribed BBs, but patients often …

β1-adrenergic receptor polymorphisms: a possible genetic predictor of bisoprolol response in acute coronary syndrome

MS Fayed, MA Saleh, NA Sabri, AA Elkholy - Future Science OA, 2023 - Future Science
Aim: To investigate the association between beta1-adrenergic receptor (ADRB1)
polymorphisms and response to bisoprolol treatment in beta-blocker naive patients with …

Association of β-adrenergic receptor gene polymorphisms with acute coronary syndrome and cardiovascular risk factors in an arab population

A El-Menyar, NM Rizk, M Asim, H Al-Thani… - …, 2016 - journals.sagepub.com
We evaluated the association between beta-adrenergic receptor genes (ADRB1 and
ADRB2) polymorphism, cardiovascular risk, and acute coronary syndrome (ACS) in …

Association of β-adrenergic receptor genes polymorphisms with incidence of subsequent cardiovascular events in Han Chinese patients with coronary artery disease

ZG Li, WU Hong, Y Zhou, ZJ Chen, JX Meng… - Chinese medical …, 2013 - journals.lww.com
Background Sequence variants in the β-adrenergic receptor (ADRB) genes have a close
relationship with the development of coronary artery disease (CAD) and the patient's …

Significant role of ADRB3 rs4994 towards the development of coronary artery disease

S Kumar, A Mishra, A Srivastava, T Mittal… - Coronary Artery …, 2014 - journals.lww.com
Background Coronary artery disease (CAD) is the most common type of heart disease and
cause of heart attacks. It has been proposed that both the susceptibility to disease and the …

Adrenergic-Pathway Gene Variants Influence Beta-Blocker–Related Outcomes After Acute Coronary Syndrome in a Race-Specific Manner

S Cresci, GW Dorn, PG Jones, AL Beitelshees… - Journal of the American …, 2012 - jacc.org
Objectives: Overcoming racial differences in acute coronary syndrome (ACS) outcomes is a
strategic goal for US health care. Genetic polymorphisms in the adrenergic pathway seem to …

[HTML][HTML] ADRB2 polymorphisms predict the risk of myocardial infarction and coronary artery disease

DW Wang, M Liu, P Wang, X Zhan, YQ Liu… - Genetics and molecular …, 2015 - SciELO Brasil
Recently, the rs1042713 G> A and rs1042714 C> G polymorphisms in the beta-2 adrenergic
receptor (ADRB2) gene were shown to be related to atherosclerosis diseases. Therefore, we …

β2-adrenergic receptor genotype and survival among patients receiving β-blocker therapy after an acute coronary syndrome

DE Lanfear, PG Jones, S Marsh, S Cresci, HL McLeod… - Jama, 2005 - jamanetwork.com
ContextPrevious data support an association between polymorphisms of the β1-and β2-
adrenergic receptors (ADRB1 and ADRB2) and surrogate end points of response to β …

β2-Adrenergic Receptor Gene Polymorphisms Are Associated with Cardiovascular Events But not All-Cause Mortality in Coronary Artery Disease Patients: A Meta …

Y Li, H Yuan, L Sun, Q Zhou, F Yang… - Genetic testing and …, 2019 - liebertpub.com
Aims: β-Adrenergic receptors (ADRBs) play a pivotal role in cardiovascular disease.
Recently, genetic polymorphisms of ADRB1 and ADRB2 have been suggested to be …

T64A polymorphism in β3‐adrenergic receptor gene (ADRB3) and coronary heart disease: a case‐cohort study and meta‐analysis

MH Zafarmand, YT Van Der Schouw… - Journal of internal …, 2008 - Wiley Online Library
Objectives. A missense mutation of the human ADRB3 gene replacing tryptophan with
arginine at codon 64 (Trp64Arg) has been related to obesity, insulin resistance, earlier onset …