Intestinal epithelia and barrier functions

JP KRAEHENBUHL, E Pringault… - Alimentary …, 1997 - Wiley Online Library
The mucosal epithelia of the digestive tract acts as a selective barrier, permeable to ions,
small molecules and macromolecules. These epithelial cells aid the digestion of food and …

Protective role of the epithelium of the small intestine and colon

PR Gibson, RP Anderson… - Inflammatory bowel …, 1996 - Wiley Online Library
The intestinal epithelium must selectively absorb nutrients but exclude luminal pathogens
and pro‐inflammatory molecules from host tissues. It is topographically organised with …

The role of the epithelial barrier in inflammatory bowel disease

EES Nieuwenhuis, RS Blumberg - Immune mechanisms in inflammatory …, 2006 - Springer
Conclusion The epithelial barrier protects the intestine from harmful antigens. The intestinal
epithelial cell produces a wide array of molecules that play a role in initiating, maintaining …

Intestinal epithelial cell regulation of mucosal inflammation

Y Yu, S Sitaraman, AT Gewirtz - Immunologic research, 2004 - Springer
The intestinal epithelium serves as one of human's primary interfaces with the outside world.
This interface is very heavily colonized with bacteria and yet permits absorption of life …

Inflammation and the intestinal barrier: leukocyte–epithelial cell interactions, cell junction remodeling, and mucosal repair

AC Luissint, CA Parkos, A Nusrat - Gastroenterology, 2016 - Elsevier
The intestinal tract is lined by a single layer of columnar epithelial cells that forms a dynamic,
permeable barrier allowing for selective absorption of nutrients, while restricting access to …

Intestinal epithelial barrier dysfunction in disease and possible therapeutical interventions

RM Catalioto, CA Maggi… - Current medicinal …, 2011 - ingentaconnect.com
The intestinal epithelial monolayer constitutes a physical and functional barrier between the
organism and the external environment. It regulates nutrients absorption, water and ion …

[图书][B] Microbial pathogenesis and the intestinal epithelial cell.

GA Hecht - 2003 - cabidigitallibrary.org
This book contains 28 papers focusing on the interactions between microbial pathogens and
the intestinal epithelial cell. The thorough and comprehensive nature of this book stems from …

The significance and potential molecular mechanisms of gastrointestinal barrier homeostasis

R Andersson, X Wang - Scandinavian journal of gastroenterology, 1997 - Taylor & Francis
The gastrointestinal barrier depends on the balance of the enteric bacterial ecology, mucus
layer, brush border, a continuous layer of polarized, columnar epithelial cells, basement …

Intestinal epithelial cells as watchdogs for the natural immune system

L Eckmann, MF Kagnoff, J Fierer - Trends in Microbiology, 1995 - cell.com
Intestinal epithelial cells secrete a spectrum of chemoattractant and proinflammatory
cytokines after invasion by bacteria. We suggest the novel concept that epithelial cells not …

[HTML][HTML] The intestinal epithelium is an integral component of a communications network

MF Kagnoff - The Journal of clinical investigation, 2014 - Am Soc Clin Investig
The epithelial lining of the intestine forms a barrier that separates the intestinal lumen from
the host's internal milieu and is critical for fluid and electrolyte secretion and nutrient …