The future of PSMA-targeted radionuclide therapy: an overview of recent preclinical research

EAM Ruigrok, WM van Weerden, J Nonnekens… - Pharmaceutics, 2019 - mdpi.com
Prostate specific membrane antigen (PSMA) has become a major focus point in the research
and development of prostate cancer (PCa) imaging and therapeutic strategies using …

Extensive preclinical evaluation of lutetium-177-labeled PSMA-specific tracers for prostate cancer radionuclide therapy

EAM Ruigrok, N van Vliet, SU Dalm, E de Blois… - European journal of …, 2021 - Springer
Purpose Various radiolabeled prostate-specific membrane antigen (PSMA)–targeting
tracers are clinically applied for prostate cancer (PCa) imaging and targeted radionuclide …

PSMA theranostics: review of the current status of PSMA-targeted imaging and radioligand therapy

W Jones, K Griffiths, PC Barata, CJ Paller - Cancers, 2020 - mdpi.com
Prostate-specific membrane antigen (PSMA) has been the subject of extensive investigation
in the past two decades as a promising molecular target for prostate cancer (PCa). Its …

Why targeting PSMA is a game changer in the management of prostate cancer

NM Donin, RE Reiter - Journal of Nuclear Medicine, 2018 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA) is a transmembrane glycoprotein that is highly
expressed on prostate adenocarcinomas, exhibits only limited expression in benign and …

PSMA-targeted radiopharmaceuticals for imaging and therapy

HJ Wester, M Schottelius - Seminars in nuclear medicine, 2019 - Elsevier
As described in more detail in other contributions in this issue of Seminars in Nuclear
Medicine, prostate-specific membrane antigen (PSMA) has become one of the most …

Imaging of nonprostate cancers using PSMA-targeted radiotracers: rationale, current state of the field, and a call to arms

RAS Fragomeni, T Amir, S Sheikhbahaei… - Journal of Nuclear …, 2018 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA) is a type II transmembrane glycoprotein that is
highly overexpressed on prostate cancer epithelial cells and for which there is a growing …

Targeting PSMA revolutionizes the role of nuclear medicine in diagnosis and treatment of prostate cancer

WI Luining, MCF Cysouw, D Meijer, NH Hendrikse… - Cancers, 2022 - mdpi.com
Simple Summary Imaging plays a crucial role in the accurate staging of prostate cancer.
Prostate-specific membrane antigen (PSMA) is overexpressed in prostate cancer cells, and …

[HTML][HTML] Towards personalized treatment of prostate cancer: PSMA I&T, a promising prostate-specific membrane antigen-targeted theranostic agent

KLS Chatalic, S Heskamp, M Konijnenberg… - Theranostics, 2016 - ncbi.nlm.nih.gov
Prostate-specific membrane antigen (PSMA) is a well-established target for nuclear imaging
and therapy of prostate cancer (PCa). Radiolabeled small-molecule PSMA inhibitors are …

PSMA targeted molecular imaging and radioligand therapy for prostate cancer: optimal patient and treatment issues

S Hoshi, K Yaginuma, S Meguro, A Onagi… - Current …, 2023 - mdpi.com
Theranostics (therapy+ diagnosis) targeting prostate-specific membrane antigen (PSMA) is
an emerging therapeutic modality that could alter treatment strategies for prostate cancer …

Radionuclide therapy in prostate cancer: from standalone to combination PSMA theranostics

S Sandhu, C Guo, MS Hofman - Journal of Nuclear Medicine, 2021 - Soc Nuclear Med
Despite significant advances in therapeutic developments for prostate cancer over the last 2
decades, metastatic prostate cancer remains a lethal disease. Prostate-specific membrane …