Mammary gland development occurs over multiple phases, beginning in the mammalian
embryo and continuing throughout reproductive life. The remarkable morphogenetic …

The mammary gland undergoes cycles of growth and regeneration throughout reproductive
life, a process that requires mammary stem cells (MaSCs). Whilst recent genetic fate …

The mammary epithelium undergoes enormous morphogenetic changes during the lifespan
of a mammal. The recent elucidation of an epithelial differentiation hierarchy in the mouse …

The mammary epithelium is highly responsive to local and systemic signals, which
orchestrate morphogenesis of the ductal tree during puberty and pregnancy. Based on …

The mammary gland is a highly dynamic organ that undergoes profound changes within its
epithelium during puberty and the reproductive cycle. These changes are fueled by …

The mammary gland consists of cells with gene expression patterns reflecting their cellular
origins, function, and spatiotemporal context. However, knowledge of developmental …

The mammary gland undergoes dynamic changes throughout life. In the mouse, these begin
with initial morphogenesis of the gland in the mid-gestation embryo followed by hormonally …

Our understanding of the molecular events underpinning the development of mammalian
organ systems has been increasing rapidly in recent years. With the advent of new and …

Postnatal mammary gland development requires the presence of mammary stem and
progenitor cells (MaSC), which give rise to functional milk‐secreting cells and regenerate …

How cells coordinate morphogenetic cues and fate specification during development
remains a fundamental question in organogenesis. The mammary gland arises from …