Clinical effectiveness of oral antiviral agents for treating non-hospitalized COVID-19 patients with chronic kidney disease

CC Chen, CY Huang, JY Wu, MY Liu… - Expert Review of Anti …, 2024 - Taylor & Francis
Objectives This study examined the effectiveness of nirmatrelvir plus ritonavir (NMV-r) and
molnupiravir (MOV) in treating COVID-19 among chronic kidney disease (CKD) patients …

Comparison of safety and efficacy between Nirmatrelvir-ritonavir and molnupiravir in the treatment of COVID-19 infection in patients with advanced kidney disease: a …

WM Chu, EYF Wan, ZCT Wong, AR Tam… - …, 2024 - thelancet.com
Background Nirmatrelvir-ritonavir is used in patients with coronavirus disease 2019 (COVID-
19) with normal or mild renal impairment (eGFR≥ 30 ml/min per 1.73 m 2). There is limited …

Safety and Efficacy of Nirmatrelvir/Ritonavir in Patients with Moderate-Severe CKD with COVID-19: A Real-World Data Study: TH-PO1095

OS Ashruf, ZC Orozco, IU Haq, Z Ashruf… - Journal of the American …, 2023 - journals.lww.com
Background: Chronic kidney disease (CKD) is a mortality risk factor for COVID-19,
predisposing patients to poor clinical outcomes. Nirmatrelvir/ritonavir (Nm/r) is currently the …

Oral antiviral therapies for COVID-19 in patients with advanced chronic kidney disease or kidney failure

WJ Cho, D Harden, D Moreno… - Nephrology Dialysis …, 2023 - academic.oup.com
As of December 2022, over 651 million people have been diagnosed with coronavirus
disease 2019 (COVID-19) and 6.6 million people have died of COVID-19 [1]. Chronic kidney …

[HTML][HTML] Effectiveness of molnupiravir and nirmatrelvir–ritonavir in CKD patients with COVID-19.

FWT Cheng, VKC Yan, EYF Wan, CSL Chui… - Kidney International …, 2024 - Elsevier
Introduction Even with effective vaccines, patients with CKD have a higher risk of
hospitalization and death subsequent to COVID-19 infection compared with those without …

Nirmatrelvir/ritonavir for patients with SARS-CoV-2 infection and impaired kidney function during the Omicron surge

J Yan, H Cai, J Wang, M Zhu, P Li, P Li, B Wu… - Frontiers in …, 2023 - frontiersin.org
Background: Nirmatrelvir/ritonavir has demonstrated effectiveness in high-risk patients with
coronavirus disease 2019 (COVID-19). However, investigations on the efficacy and safety of …

How to use COVID-19 antiviral drugs in patients with chronic kidney disease

A Kale, V Shelke, N Dagar, HJ Anders… - Frontiers in …, 2023 - frontiersin.org
Antiviral drugs such as Remdesivir (Veklury), Nirmatrelvir with Ritonavir (Paxlovid),
Azvudine, and Molnupiravir (Lagevrio) can reduce the risk for severe and fatal Coronavirus …

Safety profile and clinical and virological outcomes of nirmatrelvir-ritonavir treatment in patients with advanced chronic kidney disease and coronavirus disease 2019

GCK Chan, GCY Lui, CNS Wong… - Clinical Infectious …, 2023 - academic.oup.com
Background Nirmatrelvir-ritonavir is currently not recommended in patients with an
estimated glomerular filtration rate (eGFR)< 30 mL/minute/1.73 m2. Methods To determine …

Safety of Nirmatrelvir/Ritonavir in Dialysis Patients with COVID-19: The End of the Beginning?

OA Yilmam, DE Leaf - Clinical Journal of the American Society of …, 2023 - journals.lww.com
Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic, it has been
clear that patients with CKD and kidney failure treated with dialysis are at high risk of …

Early experience with modified dose nirmatrelvir/ritonavir in dialysis patients with coronavirus disease 2019

S Hiremath, PG Blake, A Yeung… - Clinical Journal of the …, 2023 - journals.lww.com
Background Nirmatrelvir/ritonavir was approved for use in high-risk outpatients with
coronavirus disease 2019 (COVID-19). However, patients with severe CKD were excluded …