COVID-19 has emerged as a rapidly escalating serious global health issue, affecting every
section of population in a detrimental way. Present situation invigorated researchers to look …

A novel coronavirus (SARS-CoV-2) that is initially found to trigger human severe respiratory
illness in Wuhan City of China in 2019, has killed 2,718 people in China by February 26 …

Since the outbreak emerged in November 2019, no effective drug has yet been found
against SARS-CoV-2. Repositioning studies of existing drug molecules or candidates are …

Background With few available effective interventions, emergence of novel mutants
responding poorly to existing vaccines and ever swelling newer waves of infection, SARS …

Since the outbreak of severe acute respiratory syndrome (SARS) in 2003, the harm caused
by coronaviruses to the world cannot be underestimated. Recently, a novel coronavirus …

Proceeding our prior studies of SARS-CoV-2, the inhibitory potential against SARS-CoV-2
RNA-dependent RNA polymerase (RdRp) has been investigated for a collection of 3009 …

In the current study, a structure-based virtual screening paradigm was used to screen a
small molecular database against the Non-structural protein 15 (Nsp15) endoribonuclease …

The novel coronavirus disease 2019 (COVID-19) was firstly reported from Wuhan city of
China and found as a highly contagious, transmittable and pathogenic viral infection. The …

Background: The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2), took more lives than combined …

In this study, the Nsp12–Nsp8 complex of SARS-CoV-2 was targeted with structure-based
and computer-aided drug design approach because of its vital role in viral replication …