JC Lee, M Parkes - Briefings in functional genomics, 2011 - academic.oup.com
The development of genome-wide association scanning (GWAS) has revolutionized the search for genetic loci associated with complex diseases. Crohn's disease (CD), together …
We undertook a meta-analysis of six Crohn's disease genome-wide association studies (GWAS) comprising 6,333 affected individuals (cases) and 15,056 controls and followed up …
B Verstockt, KGC Smith, JC Lee - Clinical & translational …, 2018 - Wiley Online Library
Over the course of the past decade, genome‐wide association studies (GWAS) have revolutionised our understanding of complex disease genetics. One of the diseases that has …
K Fransen, MC Visschedijk… - Human molecular …, 2010 - academic.oup.com
Genome-wide association studies (GWAS) for Crohn's disease (CD) have identified loci explaining∼ 20% of the total genetic risk of CD. Part of the other genetic risk loci is probably …
Ulcerative colitis and Crohn's disease are the two main forms of inflammatory bowel disease (IBD). Here we report the first trans-ancestry association study of IBD, with genome-wide or …
Several risk factors for Crohn's disease have been identified in recent genome-wide association studies. To advance gene discovery further, we combined data from three …
Genome-wide association scans (GWAS) using large case–control samples and several hundred thousand genetic markers have uncovered at least ten new genomic regions …
K Yamazaki, J Umeno, A Takahashi, A Hirano… - Gastroenterology, 2013 - Elsevier
BACKGROUND & AIMS: Crohn's disease is an inflammatory bowel disease induced by multiple genetic and environmental factors. Genome-wide association studies have …