The role of innate immunity in pulmonary infections

H Zhang, F He, P Li, PR Hardwidge… - BioMed Research …, 2021 - Wiley Online Library
Innate immunity forms a protective line of defense in the early stages of pulmonary infection.
The primary cellular players of the innate immunity against respiratory infections are alveolar …

Comparative analysis of the alveolar macrophage proteome in ALI/ARDS patients between the exudative phase and recovery phase

H Dong, J Li, Y Lv, Y Zhou, G Wang, S Hu, X He… - BMC immunology, 2013 - Springer
Background Despite decades of extensive studies, the morbidity and mortality for acute lung
injury/acute respiratory distress syndrome (ALI/ARDS) remained high. Particularly …

Innate immune responses and pulmonary diseases

T Liu, S Liu, X Zhou - Lung Inflammation in Health and Disease, Volume II, 2021 - Springer
Innate immunity is the first defense line of the host against various infectious pathogens,
environmental insults, and other stimuli causing cell damages. Upon stimulation, pattern …

Classic Signaling Pathways in Alveolar Injury and Repair Involved in Sepsis‐Induced ALI/ARDS: New Research Progress and Prospect

W Li, D Li, Y Chen, H Abudou, H Wang, J Cai… - Disease …, 2022 - Wiley Online Library
Sepsis is a common critical clinical disease with high mortality that can cause approximately
10 million deaths worldwide each year. Acute lung injury (ALI) or acute respiratory distress …

Gut-lung crosstalk in sepsis-induced acute lung injury

X Zhou, Y Liao - Frontiers in microbiology, 2021 - frontiersin.org
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common acute
and severe cases of the respiratory system with complicated pathogenesis and high …

Innate lymphoid cells: the role in respiratory infections and lung tissue damage

A Głobińska, ML Kowalski - Expert Review of Clinical Immunology, 2017 - Taylor & Francis
ABSTRACT Introduction: Innate lymphoid cells (ILCs) represent a diverse family of cells of
the innate immune system, which play an important role in regulation of tissue homeostasis …

[HTML][HTML] Plasmacytoid dendritic cells control lung inflammation and monocyte recruitment in indirect acute lung injury in mice

F Venet, X Huang, CS Chung, Y Chen… - The American journal of …, 2010 - Elsevier
Indirect acute lung injury (ALI, not caused by a direct insult to the lung) represents the first
organ dysfunction in trauma patients, with nonpulmonary sepsis being the most common …

Regulatory T cells in inflammation and resolution of acute lung injury

L Wang, W Jiang, X Wang, L Tong… - The Clinical Respiratory …, 2022 - Wiley Online Library
Introduction Acute respiratory distress syndrome (ARDS) is characterized by hypoxemia and
increased lung permeability and would result in acute respiratory failure and with high …

The acute respiratory distress syndrome: from mechanism to translation

SH Han, RK Mallampalli - The Journal of Immunology, 2015 - journals.aai.org
The acute respiratory distress syndrome (ARDS) is a form of severe hypoxemic respiratory
failure that is characterized by inflammatory injury to the alveolar capillary barrier, with …

Role of innate immune system in environmental lung diseases

MA Guttenberg, AT Vose, RM Tighe - Current allergy and asthma reports, 2021 - Springer
The lung mucosa functions as a principal barrier between the body and inhaled
environmental irritants and pathogens. Precise and targeted surveillance mechanisms are …