Regeneration the critical-sized bone defects remains a great challenge to clinical therapy
due to the inflammatory microenvironment and lack of stem cells in the region of the bone …

The host immune response to biomaterials is critical for determining scaffold fate and bone
regeneration outcomes. Three-dimensional (3D) bioprinted scaffolds encapsulated with …

Abstract 3D-printed biofunctional scaffolds have promising applications in bone tissue
regeneration. However, the development of bioinks with rapid internal vascularization …

Background Coordination between osteo-/angiogenesis and the osteoimmune
microenvironment is essential for effective bone repair with biomaterials. As a highly …

Due to tissue lineage variances and the anisotropic physiological characteristics,
regenerating complex osteochondral tissues (cartilage and subchondral bone) remains a …

Bioprinting is a promising technique for facilitating the fabrication of engineered bone
tissues for patient-specific defect repair and for developing in vitro tissue/organ models for …

To successfully achieve the porous cell-blocks, a bioink is a prerequisite requirement.
However, although various hydrogel-based bioinks have been applied, a …

Critical-sized bone defect repair in patients with diabetes mellitus remains a challenge in
clinical treatment because of dysfunction of macrophage polarization and the inflammatory …

Abstract Three-dimensional (3D) bioprinting is an extremely convenient biofabrication
technique for creating biomimetic tissue-engineered bone constructs and has promising …

Abstract Three-dimensional (3D) printing technology is driving forward the progresses of
various engineering fields, including tissue engineering. However, the pristine 3D-printed …