Targeting cytokine storm to manage patients with COVID-19: a mini-review

N Roshanravan, F Seif, A Ostadrahimi… - Archives of medical …, 2020 - Elsevier
Corona Virus Disease 2019 (COVID-19) pandemic is rapidly spreading all over the world.
Excessive immune responses trigger life-threatening cytokine release syndrome (CRS) …

Interleukin-6 is a biomarker for the development of fatal severe acute respiratory syndrome coronavirus 2 pneumonia

A Santa Cruz, A Mendes-Frias, AI Oliveira… - Frontiers in …, 2021 - frontiersin.org
Hyper-inflammatory responses induced by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) are a major cause of disease severity and death. Predictive prognosis …

Dysregulation of the immune response in coronavirus disease 2019

L Mohamed Khosroshahi, N Rezaei - Cell Biology International, 2021 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) can trigger a cytokine
storm in the pulmonary tissue by releasing various types of mediators, leading to acute …

Controlling cytokine storm is vital in COVID-19

L Tang, Z Yin, Y Hu, H Mei - Frontiers in immunology, 2020 - frontiersin.org
Corona virus disease 2019 (COVID-19) has caused a global outbreak and severely posed
threat to people's health and social stability. Mounting evidence suggests that …

Prospective roles of tumor necrosis factor-alpha (TNF-α) in COVID-19: prognosis, therapeutic and management

Z Mohd Zawawi, J Kalyanasundram… - International journal of …, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19) became a worldwide concern at the beginning of
2020 and has affected millions. Several previous studies revealed the impact of the …

SARS-CoV-2 Orf9b suppresses type I interferon responses by targeting TOM70

H Jiang, H Zhang, Q Meng, J Xie, Y Li… - Cellular & molecular …, 2020 - nature.com
COVID-19 is caused by SARS-CoV-2. 1 As of July 16th, 2020, there were 13,579,581
diagnosed cases and 584,782 deaths attributed to COVID-19 reported globally …

SARS-CoV-2 ORF8 protein induces endoplasmic reticulum stress-like responses and facilitates virus replication by triggering calnexin: an unbiased study

X Wang, W Wang, T Wang, J Wang, Y Jiang… - Journal of …, 2023 - Am Soc Microbiol
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the viral pathogen
responsible for the worldwide coronavirus disease 2019 (COVID-19) pandemic. The novel …

[HTML][HTML] Coronavirus disease 2019 (COVID-19): cytokine storms, hyper-inflammatory phenotypes, and acute respiratory distress syndrome

S Lin, Y Zhao, D Zhou, F Zhou, F Xu - Genes & Diseases, 2020 - Elsevier
Abstract Coronavirus Disease 2019 (COVID-19) was first identified in China at the end of
2019. Acute respiratory distress syndrome (ARDS) represents the most common and serious …

SARS-CoV-2 ORF8 forms intracellular aggregates and inhibits IFNγ-induced antiviral gene expression in human lung epithelial cells

H Geng, S Subramanian, L Wu, HF Bu… - Frontiers in …, 2021 - frontiersin.org
Infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes
COVID-19, a disease that involves significant lung tissue damage. How SARS-CoV-2 …

Attenuating the effects of novel COVID-19 (SARS-CoV-2) infection-induced cytokine storm and the implications

AB Rowaiye, OA Okpalefe… - Journal of …, 2021 - Taylor & Francis
The COVID-19 pandemic constitutes an arduous global health challenge, and the
increasing number of fatalities calls for the speedy pursuit of a remedy. This review …