Neutrophils and lymphopenia, an unknown axis in severe COVID-19 disease

HF Peñaloza, JS Lee, P Ray - PLoS pathogens, 2021 - journals.plos.org
The Coronavirus Disease 2019 (COVID-19) is caused by the betacoronavirus Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) virus that can mediate asymptomatic or …

Immunopathological roles of neutrophils in virus infection and COVID-19

SN Cui, HY Tan, GC Fan - Shock, 2021 - journals.lww.com
Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has been spread around the world and is …

SARS-CoV-2 dysregulates neutrophil degranulation and reduces lymphocyte counts

A Muralidharan, TA Wyatt, SP Reid - Biomedicines, 2022 - mdpi.com
SARS-CoV-2, the virus that causes COVID-19, has given rise to one of the largest
pandemics, affecting millions worldwide. High neutrophil-to-lymphocyte ratios have been …

Neutrophils in COVID-19: recent insights and advances

J Li, K Zhang, ye Zhang, Z Gu, C Huang - Virology journal, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is an acute respiratory disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which can lead to acute …

Neutrophils during SARS‐CoV‐2 infection: Friend or foe?

FVS Castanheira, P Kubes - Immunological Reviews, 2023 - Wiley Online Library
Summary Coronavirus disease 2019 (COVID‐19) is caused by the severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2) and has resulted in more than 6 million deaths …

Neutrophils in COVID-19: not innocent bystanders

E McKenna, R Wubben, JM Isaza-Correa… - Frontiers in …, 2022 - frontiersin.org
Unusually for a viral infection, the immunological phenotype of severe COVID-19 is
characterised by a depleted lymphocyte and elevated neutrophil count, with the neutrophil …

Neutrophils in COVID-19

N Reusch, E De Domenico, L Bonaguro… - Frontiers in …, 2021 - frontiersin.org
Strong evidence has been accumulated since the beginning of the COVID-19 pandemic that
neutrophils play an important role in the pathophysiology, particularly in those with severe …

[HTML][HTML] Activated neutrophils in the initiation and progression of COVID-19: hyperinflammation and immunothrombosis in COVID-19

X Zhao, L Zhou, Y Kou, J Kou - American Journal of Translational …, 2022 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19) is a pandemic respiratory disease caused
by a novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS …

Neutrophils and COVID-19: active participants and rational therapeutic targets

J Hazeldine, JM Lord - Frontiers in immunology, 2021 - frontiersin.org
Whilst the majority of individuals infected with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), the causative pathogen of COVID-19, experience mild to …

[HTML][HTML] Neutrophils and COVID-19: The road so far

LHA Cavalcante-Silva, DCM Carvalho… - International …, 2021 - Elsevier
The SARS-Cov2 infection triggers a multisystem inflammatory disorder, knowing as COVID-
19, a pandemic disease. This disease is characterized by acute respiratory distress …