We used patch-clamp electrophysiology on isolated, split-open murine collecting ducts (CD)
to test the hypothesis that regulation of epithelial sodium channel (ENaC) activity is a …

Sodium transport is increased by vasopressin in the cortical collecting ducts of rats and
rabbits. Here we investigate, by quantitative immunoblotting, the effects of vasopressin on …

Water balance is achieved through the ability of the kidney to control water reabsorption in
the connecting tubule and the collecting duct. In a mouse cortical collecting duct cell line …

Tubular reabsorption of filtered sodium is tightly controlled to maintain body volume
homeostasis. The rate of sodium transport by collecting duct (CD) cells varies widely in …

Vasopressin promotes renal water reabsorption decreasing excretion of free water to dilute
plasma and lower serum osmolality. We have good understanding of the causes …

Vectorial Na+ absorption across the aldosterone-sensitive distal nephron plays a key role in
the regulation of extracellular fluid volume and blood pressure. Within this nephron segment …

Hyponatremia is associated with inappropriately elevated vasopressin levels. A brisk
natriuresis precedes the escape from this antidiuresis. Thus, the hypothesis was that the …

Vasopressin is known to acutely stimulate sodium transport in the renal collecting duct. We
investigated the long-term regulation by vasopressin of the epithelial sodium channel …

Previous studies revealed that chronic (days) vasopressin treatment stimulates amiloride-
sensitive sodium transport in isolated renal cortical collecting ducts and increases the …

Arginine-vasopressin (AVP) stimulates Na+ transport and Na-K-ATPase activity via cAMP-
dependent PKA activation in the renal cortical collecting duct (CCD). We investigated the …