Increased knowledge of the biology of synaptic function has led to the development of novel
cognitive-enhancing therapeutic strategies with the potential for increased efficacy and …

Brain aging and aging-related neurodegenerative disorders are posing a significant
challenge for health systems worldwide. To date, most of the therapeutic efforts aimed at …

The rapid aging of populations around the world has become an unprecedented challenge.
Aging is associated with cognitive impairment, including dementia and mild cognitive …

An unfortunate result of the rapid rise in geriatric populations worldwide is the increasing
prevalence of age-related cognitive disorders such as Alzheimer's disease (AD). AD is a …

This review summarizes the scientific talks presented at the conference “Therapeutics for
Cognitive Aging,” hosted by the New York Academy of Sciences and the Alzheimer's Drug …

A cascade of pathophysiogical events is triggered in Alzheimer's disease (AD) that ultimately
involves common cellular signaling pathways and leads to cellular and network dysfunction …

Alzheimer's disease is a progressive neurodegenerative disorder and the leading cause of
dementia in the Western world. Postmortem, it is characterized neuropathologically by the …

Memory, cognition, dementia, and neurodegeneration are complexly interlinked processes
with various mechanistic pathways, leading to a range of clinical outcomes. They are …

Neurodegenerative disorders involve progressive dysfunction and loss of synapses and
neurons and brain atrophy, slowly declining memories and cognitive skills, throughout a …

Recently, pharmacological research has shifted from pathophysiological causes of diseases
associated with cognitive disorders such as attention deficit hyperactivity disorder …